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Cellosaurus HT52 (CVCL_A8FH)

[Text version]
Cell line name HT52
Accession CVCL_A8FH
Resource Identification Initiative To cite this cell line use: HT52 (RRID:CVCL_A8FH)
Comments Monoclonal antibody isotype: IgG1, kappa.
Monoclonal antibody target: UniProtKB; O00206; Human TLR4.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Hierarchy Parent: CVCL_2199 (Sp2/0-Ag14)
Category Hybridoma
Publications

PubMed=22499954; DOI=10.1093/intimm/dxs053
Hiroki Tsukamoto, Kenji Fukudome, Shoko Takao, Naoko Tsuneyoshi, Hideyuki Ihara, Yoshitaka Ikeda, Masao Kimoto;
Multiple potential regulatory sites of TLR4 activation induced by LPS as revealed by novel inhibitory human TLR4 mAbs.
Int. Immunol. 24:495-506(2012)

PubMed=26602081; DOI=10.1016/j.febslet.2015.11.018
Hiroki Tsukamoto, Ippo Ukai, Yuki Yamagata, Shino Takeuchi, Kanae Kubota, Sao Kozakai, Naoto Suzuki, Masao Kimoto, Yoshihisa Tomioka;
Leucine-rich repeat 2 of human Toll-like receptor 4 contains the binding site for inhibitory monoclonal antibodies.
FEBS Lett. 589:3893-3898(2015)

PubMed=28741733; DOI=10.1002/1873-3468.12768
Hiroki Tsukamoto, Yuki Yamagata, Ippo Ukai, Shino Takeuchi, Misaki Okubo, Yohei Kobayashi, Sao Kozakai, Kanae Kubota, Muneo Numasaki, Yoshitomi Kanemitsu, Yotaro Matsumoto, Yoshihisa Tomioka;
An inhibitory epitope of human Toll-like receptor 4 resides on leucine-rich repeat 13 and is recognized by a monoclonal antibody.
FEBS Lett. 591:2406-2416(2017)

Cross-references
Encyclopedic resources Wikidata; Q107115379
Entry history
Entry creation20-May-2021
Last entry update21-Mar-2023
Version number3