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Cellosaurus HEK-Dual IFN-gamma (CVCL_A8CY)

[Text version]
Cell line name HEK-Dual IFN-gamma
Accession CVCL_A8CY
Resource Identification Initiative To cite this cell line use: HEK-Dual IFN-gamma (RRID:CVCL_A8CY)
Comments Characteristics: Allows the detection of bioactive human IFN-gamma by monitoring the activation of the JAK/STAT1 pathway.
Characteristics: Stably expresses two reporter genes: SEAP (secreted ALPP) and the Lucia luciferase. In this cell line both genes are under the control of an ISG54 minimal promoter in conjunction with four IFN-gamma activated sites (GAS).
Transfected with: HGNC; 439; ALPP.
Transfected with: HGNC; 11362; STAT1.
Transfected with: Lucia luciferase, a synthetic gene designed on natural secreted luciferase genes from marine copepods.
Transfected with: UniProtKB; P33967; B.cereus Bsr.
Transfected with: UniProtKB; P17493; Streptoalloteichus hindustanus ble (BleoR).
Transfected with: UniProtKB; P13249; S.alboniger pac (PuroR).
Transformant: NCBI_TaxID; 28285; Adenovirus 5.
Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0045 (HEK293)
Sex of cell Female
Age at sampling Fetus
Category Transformed cell line
Web pages https://www.invivogen.com/hek-dual-ifn-g
Cross-references
Encyclopedic resources Wikidata; Q107115294
Entry history
Entry creation20-May-2021
Last entry update05-Oct-2023
Version number6