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Cellosaurus CHB-11 (CVCL_A822)

[Text version]

Cell line name CHB-11
Synonyms CHB11; BCHe005-A
Accession CVCL_A822
Resource Identification Initiative To cite this cell line use: CHB-11 (RRID:CVCL_A822)
Comments From: Children's Hospital Boston; Boston; USA.
Registration: NIH Human Embryonic Stem Cell Registry; NIHhESC-10-0010.
Omics: Deep exome analysis.
Omics: SNP array analysis.
Sequence variations
  • Mutation; HGNC; 11998; TP53; Simple; p.Arg175His (c.524G>A); ClinVar=VCV000012374; Zygosity=Unspecified; Note=Somatic mutation acquired during proliferation (PubMed=28445466).
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling Blastocyst stage
Category Embryonic stem cell
Web pages https://grants.nih.gov/stem_cells/registry/current.htm?id=13

PubMed=18223642; DOI=10.1038/nbt1378
Lerou P.H., Yabuuchi A., Huo H.-G., Takeuchi A., Shea J., Cimini T., Ince T.A., Ginsburg E., Racowsky C., Daley G.Q.
Human embryonic stem cell derivation from poor-quality embryos.
Nat. Biotechnol. 26:212-214(2008)

PubMed=28445466; DOI=10.1038/nature22312
Merkle F.T., Ghosh S., Kamitaki N., Mitchell J., Avior Y., Mello C., Kashin S., Mekhoubad S., Ilic D., Charlton M., Saphier G., Handsaker R.E., Genovese G., Bar S., Benvenisty N., McCarroll S.A., Eggan K.C.
Human pluripotent stem cells recurrently acquire and expand dominant negative P53 mutations.
Nature 545:229-233(2017)

Cell line databases/resources hPSCreg; BCHe005-A
ISCR; 76
SKIP; SKIP001988
Encyclopedic resources Wikidata; Q54811743
Entry history
Entry creation06-Jun-2012
Last entry update20-May-2021
Version number15