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Cellosaurus U2OS EGFP-H2B (CVCL_A7QQ)

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Cell line name U2OS EGFP-H2B
Accession CVCL_A7QQ
Resource Identification Initiative To cite this cell line use: U2OS EGFP-H2B (RRID:CVCL_A7QQ)
Comments Population: Caucasian.
Genetic integration: Method=Transfection/transduction; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP).
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:4761; H2BC11.
Derived from site: In situ; Bone, tibia; UBERON=UBERON_0000979.
Sequence variations
  • Mutation; HGNC; HGNC:9277; PPM1D; Simple; p.Arg458Ter (c.1372C>T); ClinVar=VCV002445214; Zygosity=Heterozygous (from parent cell line).
Disease Osteosarcoma (NCIt: C9145)
Osteosarcoma (ORDO: Orphanet_668)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0042 (U2OS)
Sex of cell Female
Age at sampling 15Y
Category Cancer cell line
STR profile Source(s): Millipore=SCC293

Markers:
AmelogeninX
CSF1PO12,13
D3S135816
D5S8188,11
D7S82011,12
D8S117912,14
D13S31713
D16S53911,12
D18S5112,14
D21S1131
FGA20
Penta D9
Penta E10,13
TH016,9.3
TPOX11,12
vWA14,18

Run an STR similarity search on this cell line
Publications

PubMed=28415769; DOI=10.18632/oncotarget.16225; PMCID=PMC5564716
Hai-Bo Wang, Bin Peng, Raj Kumari Pandita, David A. Engler, Rise K. Matsunami, Xing-Zhi Xu, Pavana M. Hegde, Brian E. Butler, Tej K. Pandita, Sankar Mitra, Bo Xu, Muralidhar L. Hegde;
Aurora kinase B dependent phosphorylation of 53BP1 is required for resolving merotelic kinetochore-microtubule attachment errors during mitosis.
Oncotarget 8:48671-48687(2017)

Cross-references
Cell line collections (Providers) Millipore; SCC293
Encyclopedic resources Wikidata; Q107117173
Entry history
Entry creation20-May-2021
Last entry update10-Apr-2025
Version number10