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Cellosaurus PF130 (CVCL_A7EV)

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Cell line name PF130
Accession CVCL_A7EV
Resource Identification Initiative To cite this cell line use: PF130 (RRID:CVCL_A7EV)
Comments Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Mutation; HGNC; HGNC:6840; MAP2K1; Simple; p.Glu102_Lys104delinsGln (c.303_310del8ins); Zygosity=Unspecified (PubMed=33669371).
Disease Spitz melanoma (NCIt: C165497)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 37Y
Category Cancer cell line
Publications

PubMed=33669371; DOI=10.3390/cancers13040829; PMCID=PMC7920251
Luca Hegedus, Ozlem Okumus, Elisabeth Livingstone, Marcell Baranyi, Ildiko Kovacs, Balazs Dome, Jozsef Tovari, Agnes Bankfalvi, Dirk Schadendorf, Clemens Aigner, Balazs Hegedus;
Allosteric and ATP-competitive MEK-inhibition in a novel spitzoid melanoma model with a RAF- and phosphorylation-independent mutation.
Cancers (Basel) 13:829.1-829.12(2021)

Cross-references
Encyclopedic resources Wikidata; Q107116657
Entry history
Entry creation20-May-2021
Last entry update19-Dec-2024
Version number5