Cellosaurus cell line UT-SCC-110A (CVCL

Cellosaurus UT-SCC-110A (CVCL_A7EB)

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Cell line name

UT-SCC-110A

Synonyms

University of Turku-Squamous Cell Carcinoma-110B

Accession

CVCL_A7EB

Resource Identification Initiative

To cite this cell line use: UT-SCC-110A (RRID:CVCL_A7EB)

Comments

Omics: Genomics; Whole exome sequencing.
Omics: Transcriptomics; Microarray.
Omics: Variations; Array-based CGH.
Derived from site: In situ; Nose, nasal cavity, maxillary sinus; UBERON=UBERON_0001764.

Sequence variations

Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg342Ter (c.1024C>T); ClinVar=VCV000182970; Zygosity=Homozygous (PubMed=29970484).

Disease

Maxillary sinus squamous cell carcinoma (NCIt: C6064)
Squamous cell carcinoma of the nasal cavity and paranasal sinuses (ORDO: Orphanet_500464)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Originate from same individual

CVCL_A091 ! UT-SCC-110B

Sex of cell

Male

Age at sampling

37Y

Category

Cancer cell line

STR profile

Source(s): PubMed=30135316

Markers:

Amelogenin	X
CSF1PO	10,11
D2S1338	20
D3S1358	14,17
D5S818	11
D7S820	9,12
D8S1179	11,14
D13S317	8
D16S539	11,12
D18S51	13,16,17
D19S433	14,16
D21S11	31,31.2
FGA	20
TH01	8
TPOX	8,10
vWA	16,17

Publications

PubMed=29970484; DOI=10.1158/1535-7163.MCT-17-0733
Tatiana Lepikhova, Piia-Riitta Karhemo, Riku Louhimo, Bhagwan Yadav, Astrid Murumagi, Evgeny Kulesskiy, Mikko Kivento, Harri Sihto, Reidar Grenman, Stina M. Syrjanen, Olli-Pekka Kallioniemi ...Show all 15 authors... , Tero Aittokallio, Krister Wennerberg, Heikki Joensuu, Outi Monni; Show fewer authors
Drug-sensitivity screening and genomic characterization of 45 HPV-negative head and neck carcinoma cell lines for novel biomarkers of drug efficacy.
Mol. Cancer Ther. 17:2060-2071(2018)

PubMed=30135316; DOI=10.1172/jci.insight.122204; PMCID=PMC6141174
Stephen M.F. Jamieson, Peter Tsai, Maria K. Kondratyev, Pratha Budhani, Arthur Liu, Neil N. Senzer, E. Gabriela Chiorean, Shadia I. Jalal, John Joseph Nemunaitis, Dennis Kee, Avik Shome ...Show all 35 authors... , Way W. Wong, Dan Li, Nooriyah Poonawala-Lohani, Purvi M. Kakadia, Nicholas S. Knowlton, Courtney R.H. Lynch, Cho R. Hong, Tet Woo Lee, Reidar Grenman, Laura Caporiccio, Trevor David McKee, Mark Zaidi, Sehrish Butt, Andrew M.J. Macann, Nicholas P. McIvor, John M. Chaplin, Kevin O. Hicks, Stefan Klaus Bohlander, Bradly G. Wouters, Charles P. Hart, Cristin Gregor Print, William R. Wilson, Michael A. Curran, Francis W. Hunter; Show fewer authors
Evofosfamide for the treatment of human papillomavirus-negative head and neck squamous cell carcinoma.
JCI Insight 3:e122204.1-e122204.19(2018)

DOI=10.1158/1538-7445.AM2020-507
Maria K. Kondratyev, Aleksandra Pesic, Anna Dvorkin-Sheva, Troy Ketela, Jason Moffat, Marianne Koritzinsky, Bradly G. Wouters;
Repurposing of FDA approved drugs for treatment of metastatic HNSCC.
Cancer Res. 80 Suppl. 16:507-507(2020)

Cross-references

Cell line databases/resources

cancercelllines; CVCL_A7EB

Encyclopedic resources

Wikidata; Q107117358

Gene expression databases

GEO; GSM2883394
GEO; GSM2888857

Entry history

Entry creation

20-May-2021

Last entry update

10-Apr-2025

Version number