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Cellosaurus UT-SCC-76B (CVCL_A7EA)

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Cell line name UT-SCC-76B
Synonyms University of Turku-Squamous Cell Carcinoma-76B
Accession CVCL_A7EA
Resource Identification Initiative To cite this cell line use: UT-SCC-76B (RRID:CVCL_A7EA)
Comments Omics: Genomics; Whole exome sequencing.
Caution: UT-SCC-76A and UT-SCC-76B are supposed to originate from the same patient but have totally different STR profiles.
Derived from site: In situ; Oral cavity, tongue; UBERON=UBERON_0001723.
Disease Tongue squamous cell carcinoma (NCIt: C4648)
Squamous cell carcinoma of the oral tongue (ORDO: Orphanet_457252)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_A7DZ ! UT-SCC-76A
Sex of cell Male
Age at sampling >52Y
Category Cancer cell line
STR profile Source(s): PubMed=30135316

Markers:
AmelogeninX,Y
CSF1PO11,12
D2S133819,24
D3S135817
D5S81811,12
D7S8208,11
D8S117910,13
D13S31713
D16S5399,12
D18S5119
D19S43313
D21S1128,30
FGA24
TH016,9.3
TPOX8,11
vWA17,18

Run an STR similarity search on this cell line
Publications

PubMed=30135316; DOI=10.1172/jci.insight.122204; PMCID=PMC6141174
Stephen M.F. Jamieson, Peter Tsai, Maria K. Kondratyev, Pratha Budhani, Arthur Liu, Neil N. Senzer, E. Gabriela Chiorean, Shadia I. Jalal, John Joseph Nemunaitis, Dennis Kee, Avik Shome ...Show all 35 authors... , Way W. Wong, Dan Li, Nooriyah Poonawala-Lohani, Purvi M. Kakadia, Nicholas S. Knowlton, Courtney R.H. Lynch, Cho R. Hong, Tet Woo Lee, Reidar Grenman, Laura Caporiccio, Trevor David McKee, Mark Zaidi, Sehrish Butt, Andrew M.J. Macann, Nicholas P. McIvor, John M. Chaplin, Kevin O. Hicks, Stefan Klaus Bohlander, Bradly G. Wouters, Charles P. Hart, Cristin Gregor Print, William R. Wilson, Michael A. Curran, Francis W. Hunter; Show fewer authors
Evofosfamide for the treatment of human papillomavirus-negative head and neck squamous cell carcinoma.
JCI Insight 3:e122204.1-e122204.19(2018)

DOI=10.1158/1538-7445.AM2020-507
Maria K. Kondratyev, Aleksandra Pesic, Anna Dvorkin-Sheva, Troy Ketela, Jason Moffat, Marianne Koritzinsky, Bradly G. Wouters;
Repurposing of FDA approved drugs for treatment of metastatic HNSCC.
Cancer Res. 80 Suppl. 16:507-507(2020)

Cross-references
Encyclopedic resources Wikidata; Q107117383
Entry history
Entry creation20-May-2021
Last entry update10-Apr-2025
Version number5