Cellosaurus cell line MEF_Hsp47 KO-11 (CVCL

Cross-references
Cell line name	MEF_Hsp47 KO-11
Accession	CVCL_A7BD
Resource Identification Initiative	To cite this cell line use: MEF_Hsp47 KO-11 (RRID:CVCL_A7BD)
Comments	Knockout cell: Method=KO mouse; MGI; MGI:88283; Serpinh1. Derived from site: In situ; Embryo; UBERON=UBERON_0000922. Cell type: Fibroblast; CL=CL_0000057.
Species of origin	Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Sex of cell	Sex unspecified
Age at sampling	8-9FD
Category	Spontaneously immortalized cell line
Publications	PubMed=10995453; DOI=10.1083/jcb.150.6.1499; PMCID=PMC2150697 Naoko Nagai, Masanori Hosokawa, Shigeyoshi Itohara, Eijiro Adachi, Takatoshi Matsushita, Nobuko Hosokawa, Kazuhiro Nagata; Embryonic lethality of molecular chaperone hsp47 knockout mice is associated with defects in collagen biosynthesis. J. Cell Biol. 150:1499-1506(2000) PubMed=16525016; DOI=10.1091/mbc.e05-11-1065; PMCID=PMC1446091 Yoshihito Ishida, Hiroshi Kubota, Akitsugu Yamamoto, Akira Kitamura, Hans Peter Bachinger, Kazuhiro Nagata; Type I collagen in Hsp47-null cells is aggregated in endoplasmic reticulum and deficient in N-propeptide processing and fibrillogenesis. Mol. Biol. Cell 17:2346-2355(2006)
Cell line collections (Providers)	RCB; RCB5292
Encyclopedic resources	Wikidata; Q107116337
Entry history
Entry creation	20-May-2021
Last entry update	29-Jun-2023
Version number	6