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Cellosaurus HEK-DsupKD (CVCL_A7AX)

[Text version]
Cell line name HEK-DsupKD
Accession CVCL_A7AX
Resource Identification Initiative To cite this cell line use: HEK-DsupKD (RRID:CVCL_A7AX)
Comments Characteristics: Expresses Dsup under the control of a constitutive CAG promoter (PubMed=27649274).
Knockout cell: Method=shRNA knockdown; UniProtKB; P0DOW4; Ramazzottius varieornatus Dsup.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Genetic integration: Method=Transfection; Gene=UniProtKB; P0DOW4; Ramazzottius varieornatus Dsup.
Genetic integration: Method=Transfection; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Transformant: NCBI_TaxID; 28285; Human adenovirus C serotype 5.
Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_A7AW (HEK-Dsup)
Sex of cell Female
Age at sampling Fetus
Category Transformed cell line
Publications

PubMed=27649274; DOI=10.1038/ncomms12808; PMCID=PMC5034306
Takuma Hashimoto, Daiki D. Horikawa, Yuki Saito, Hirokazu Kuwahara, Hiroko Kozuka-Hata, Tadasu Shin-I, Yohei Minakuchi, Kazuko Ohishi, Ayuko Motoyama, Tomoyuki Aizu, Atsushi Enomoto ...Show all 28 authors... , Koyuki Kondo, Sae Tanaka, Yuichiro Hara, Shigeyuki Koshikawa, Hiroshi Sagara, Toru Miura, Shin-ichi Yokobori, Kiyoshi Miyagawa, Yutaka Suzuki, Takeo Kubo, Masaaki Oyama, Yuji Kohara, Asao Fujiyama, Kazuharu Arakawa, Toshiaki Katayama, Atsushi Toyoda, Takekazu Kunieda; Show fewer authors
Extremotolerant tardigrade genome and improved radiotolerance of human cultured cells by tardigrade-unique protein.
Nat. Commun. 7:12808.1-12808.14(2016)

Cross-references
Cell line collections (Providers) RCB; RCB4688
Encyclopedic resources Wikidata; Q107115288
Entry history
Entry creation20-May-2021
Last entry update14-Aug-2025
Version number7