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Cellosaurus SCL-I (CVCL_A789)

[Text version]
Cell line name SCL-I
Synonyms SCL I; SCL-1; SCL1
Accession CVCL_A789
Resource Identification Initiative To cite this cell line use: SCL-I (RRID:CVCL_A789)
Comments Population: Caucasian.
Doubling time: ~50-60 hours (CLS=300496).
Derived from site: In situ; Face, skin; UBERON=UBERON_1000021.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Val197Ter; Zygosity=Unspecified (PubMed=11992403).
Disease Skin squamous cell carcinoma (NCIt: C4819)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_A0CN (SCL1-CD4 clone 6)
Sex of cell Female
Age at sampling 74Y
Category Cancer cell line
STR profile Source(s): CLS=300496

Markers:
AmelogeninX
CSF1PO10,11
D3S135816,17
D5S81811,12
D7S82011
D8S117913,14
D13S3179,11
D16S5399,12
D18S5116,19
D21S1129,30
FGA21
Penta D13,14
Penta E12
TH016,9.3
TPOX8,11
vWA16,18

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Publications

PubMed=6950169; DOI=10.1093/jnci/68.3.415
Petra Boukamp, Wolfgang Tilgen, Rule T. Dzarlieva-Petrusevska, Dirk Breitkreutz, Dietrich Haag, Rudiger K. Riehl, Axel Bohnert, Norbert E. Fusenig;
Phenotypic and genotypic characteristics of a cell line from a squamous cell carcinoma of human skin.
J. Natl. Cancer Inst. 68:415-427(1982)

PubMed=6196111
Wolfgang Tilgen, Petra Boukamp, Dirk Breitkreutz, Rule T. Dzarlieva-Petrusevska, Monika Engstner, Dietrich Haag, Norbert E. Fusenig;
Preservation of morphological, functional, and karyotypic traits during long-term culture and in vivo passage of two human skin squamous cell carcinomas.
Cancer Res. 43:5995-6011(1983)

PubMed=2293663; DOI=10.1128/JVI.64.1.215-221.1990; PMCID=PMC249089
Bruce W. Chesebro, Richard Buller, John Lee Portis, Kathy Wehrly;
Failure of human immunodeficiency virus entry and infection in CD4-positive human brain and skin cells.
J. Virol. 64:215-221(1990)

PubMed=11992403; DOI=10.1002/ijc.10321
Susanne Popp, Stefan Waltering, Christel Herbst, Ingrid Moll, Petra Boukamp;
UV-B-type mutations and chromosomal imbalances indicate common pathways for the development of Merkel and skin squamous cell carcinomas.
Int. J. Cancer 99:352-360(2002)

Cross-references
Cell line collections (Providers) CLS; 300496
Chemistry resources ChEMBL-Cells; CHEMBL3307442
ChEMBL-Targets; CHEMBL614903
PubChem_Cell_line; CVCL_A789
Encyclopedic resources Wikidata; Q54952439
Polymorphism and mutation databases Cosmic; 740987
Entry history
Entry creation06-Jun-2012
Last entry update19-Dec-2024
Version number18