| Cell line name |
SCL-I |
| Synonyms |
SCL I; SCL-1; SCL1 |
| Accession |
CVCL_A789 |
| Resource Identification Initiative |
To cite this cell line use: SCL-I (RRID:CVCL_A789) |
| Comments |
Population: Caucasian. Doubling time: ~50-60 hours (CLS=300496). Derived from site: In situ; Face, skin; UBERON=UBERON_1000021. |
| Sequence variations |
- Mutation; HGNC; HGNC:11998; TP53; Simple; p.Val197Ter; Zygosity=Unspecified (PubMed=11992403).
|
| Disease |
Skin squamous cell carcinoma (NCIt: C4819) |
| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
| Hierarchy |
Children:
|
| Sex of cell |
Female |
| Age at sampling |
74Y |
| Category |
Cancer cell line |
| STR profile |
Source(s): CLS=300496
Markers:| Amelogenin | X |
| CSF1PO | 10,11 |
| D3S1358 | 16,17 |
| D5S818 | 11,12 |
| D7S820 | 11 |
| D8S1179 | 13,14 |
| D13S317 | 9,11 |
| D16S539 | 9,12 |
| D18S51 | 16,19 |
| D21S11 | 29,30 |
| FGA | 21 |
| Penta D | 13,14 |
| Penta E | 12 |
| TH01 | 6,9.3 |
| TPOX | 8,11 |
| vWA | 16,18 |
Run an STR similarity search on this cell line |
| Publications | PubMed=6950169; DOI=10.1093/jnci/68.3.415 Petra Boukamp, Wolfgang Tilgen, Rule T. Dzarlieva-Petrusevska, Dirk Breitkreutz, Dietrich Haag, Rudiger K. Riehl, Axel Bohnert, Norbert E. Fusenig; Phenotypic and genotypic characteristics of a cell line from a squamous cell carcinoma of human skin. J. Natl. Cancer Inst. 68:415-427(1982) PubMed=6196111 Wolfgang Tilgen, Petra Boukamp, Dirk Breitkreutz, Rule T. Dzarlieva-Petrusevska, Monika Engstner, Dietrich Haag, Norbert E. Fusenig; Preservation of morphological, functional, and karyotypic traits during long-term culture and in vivo passage of two human skin squamous cell carcinomas. Cancer Res. 43:5995-6011(1983) PubMed=2293663; DOI=10.1128/JVI.64.1.215-221.1990; PMCID=PMC249089 Bruce W. Chesebro, Richard Buller, John Lee Portis, Kathy Wehrly; Failure of human immunodeficiency virus entry and infection in CD4-positive human brain and skin cells. J. Virol. 64:215-221(1990) PubMed=11992403; DOI=10.1002/ijc.10321 Susanne Popp, Stefan Waltering, Christel Herbst, Ingrid Moll, Petra Boukamp; UV-B-type mutations and chromosomal imbalances indicate common pathways for the development of Merkel and skin squamous cell carcinomas. Int. J. Cancer 99:352-360(2002) |
| Cross-references |
| Cell line collections (Providers) |
CLS; 300496
|
| Chemistry resources |
ChEMBL-Cells; CHEMBL3307442
ChEMBL-Targets; CHEMBL614903
PubChem_Cell_line; CVCL_A789
|
| Encyclopedic resources |
Wikidata; Q54952439
|
| Polymorphism and mutation databases |
Cosmic; 740987
|
| Entry history |
| Entry creation | 06-Jun-2012 |
| Last entry update | 19-Dec-2024 |
| Version number | 18 |
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