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Cellosaurus ARK (CVCL_A760)

[Text version]
Cell line name ARK
Synonyms Ark; ark; ARK-B
Accession CVCL_A760
Resource Identification Initiative To cite this cell line use: ARK (RRID:CVCL_A760)
Comments Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
Cell type: Plasma cell; CL=CL_0000786.
Sequence variations
Disease Plasma cell myeloma (NCIt: C3242)
Multiple myeloma (ORDO: Orphanet_29073)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=8427968; DOI=10.1182/blood.V81.3.767.767
Ronnie Cato Ridley, Hui-Qing Xiao, Hiroyuki Hata, Jeff Woodliff, Joshua Epstein, Ralph D. Sanderson;
Expression of syndecan regulates human myeloma plasma cell adhesion to type I collagen.
Blood 81:767-774(1993)

PubMed=8051085; DOI=10.1016/S0021-9258(17)32120-8
Brian F. Liebersbach, Ralph D. Sanderson;
Expression of syndecan-1 inhibits cell invasion into type I collagen.
J. Biol. Chem. 269:20013-20019(1994)

PubMed=8943038; DOI=10.1073/pnas.93.24.13931; PMCID=PMC19472
Peter Leif Bergsagel, Marta Chesi, Elena Nardini, Leslie A. Brents, Suzanne Lee Kirby, Walter Michael Kuehl;
Promiscuous translocations into immunoglobulin heavy chain switch regions in multiple myeloma.
Proc. Natl. Acad. Sci. U.S.A. 93:13931-13936(1996)

DOI=10.1007/0-306-46877-8_4
Helena Jernberg-Wiklund, Kenneth Nilsson;
Multiple myeloma cell lines.
(In book chapter) Human cell culture. Vol. 3. Cancer cell lines part 3; Masters, John R.W. & Palsson, Bernhard Orn (eds.); pp.81-155; Kluwer Academic Publishers; New York; USA (2000)

PubMed=10936422; DOI=10.1016/S0145-2126(99)00195-2
Hans Gunther Drexler, Yoshinobu Matsuo;
Malignant hematopoietic cell lines: in vitro models for the study of multiple myeloma and plasma cell leukemia.
Leuk. Res. 24:681-703(2000)

PubMed=11001907; DOI=10.1182/blood.V96.7.2528
Magne Borset, Oyvind Hjertner, Shmuel Yaccoby, Joshua Epstein, Ralph D. Sanderson;
Syndecan-1 is targeted to the uropods of polarized myeloma cells where it promotes adhesion and sequesters heparin-binding proteins.
Blood 96:2528-2536(2000)

PubMed=11157491; DOI=10.1182/blood.V97.3.729
Marta Chesi, Leslie A. Brents, Sarah A. Ely, Carlos Bais, Davide F. Robbiani, Enrique A. Mesri, Walter Michael Kuehl, Peter Leif Bergsagel;
Activated fibroblast growth factor receptor 3 is an oncogene that contributes to tumor progression in multiple myeloma.
Blood 97:729-736(2001)

PubMed=11167840; DOI=10.1046/j.1365-2141.2001.02531.x
Maurizio Chiriva-Internati, Jian-Hui Du, Martin Cannon, Bart Barlogie, Qing Yi;
Myeloma-reactive allospecific cytotoxic T lymphocytes lyse target cells via the granule exocytosis pathway.
Br. J. Haematol. 112:410-420(2001)

PubMed=14555701
Masood A. Shammas, Robert Joseph Shmookler Reis, Masaharu Akiyama, Hemanta Koley, Dharminder Chauhan, Teru Hideshima, Raj K. Goyal, Laurence H. Hurley, Kenneth Carl Anderson, Nikhil C. Munshi;
Telomerase inhibition and cell growth arrest by G-quadruplex interactive agent in multiple myeloma.
Mol. Cancer Ther. 2:825-833(2003)

PubMed=15381930; DOI=10.1038/sj.bjc.6602160; PMCID=PMC2409933
Zhi-Qing Wang, Y. Zhang, Bernard Ramsahoye, Derrick John Bowen, Seah H. Lim;
Sp17 gene expression in myeloma cells is regulated by promoter methylation.
Br. J. Cancer 91:1597-1603(2004)

Cross-references
Cell line databases/resources cancercelllines; CVCL_A760
Anatomy/cell type resources BTO; BTO_0003930
Encyclopedic resources Wikidata; Q54750449
Polymorphism and mutation databases Cosmic; 720774
Cosmic; 760398
Cosmic; 2302413
Cosmic; 2367270
Entry history
Entry creation06-Jun-2012
Last entry update14-Aug-2025
Version number19