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Cellosaurus VMM15 (CVCL_A736)

[Text version]
Cell line name VMM15
Accession CVCL_A736
Resource Identification Initiative To cite this cell line use: VMM15 (RRID:CVCL_A736)
Comments Population: Caucasian.
Omics: Genomics; Whole exome sequencing.
Omics: Transcriptomics; Microarray.
Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000029.
Sequence variations
HLA typing Source: PubMed=10752474
Class I
HLA-AA*01,25
HLA-BB*08,18
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 39Y
Category Cancer cell line
STR profile Source(s): ATCC=CRL-3227

Markers:
AmelogeninX
CSF1PO10
D5S8189,15
D7S82010,12
D13S31712
D16S53912
TH016
TPOX8
vWA17,18

Run an STR similarity search on this cell line
Publications

PubMed=10752474; DOI=10.1007/s002620050015; PMCID=PMC11037162
Craig L. Slingluff Jr., Teresa A. Colella, Lee Thompson, D. David Graham, Jonathan C.A. Skipper, Jennifer Caldwell, Larry Brinckerhoff, David J. Kittlesen, Donna H. Deacon, Correen Oei, Nancy L. Harthun ...Show all 15 authors... , Eric L. Huczko, Donald Frederick Hunt, Timothy L. Darrow, Victor H. Engelhard; Show fewer authors
Melanomas with concordant loss of multiple melanocytic differentiation proteins: immune escape that may be overcome by targeting unique or undefined antigens.
Cancer Immunol. Immunother. 48:661-672(2000)

PubMed=14871852; DOI=10.1158/0008-5472.CAN-03-2209
Kevin T. Hogan, Michael A. Coppola, Christine L. Gatlin, Lee W. Thompson, Jeffrey Shabanowitz, Donald Frederick Hunt, Victor H. Engelhard, Mark M. Ross, Craig L. Slingluff Jr.;
Identification of novel and widely expressed cancer/testis gene isoforms that elicit spontaneous cytotoxic T-lymphocyte reactivity to melanoma.
Cancer Res. 64:1157-1163(2004)

PubMed=20856146; DOI=10.1097/CMR.0b013e32833fafb4; PMCID=PMC3229868
Leann M. Mikesh, Manish Kumar, Gulsun Erdag, Kevin T. Hogan, Kerrington R. Molhoek, Marty W. Mayo, Craig L. Slingluff Jr.;
Evaluation of molecular markers of mesenchymal phenotype in melanoma.
Melanoma Res. 20:485-495(2010)

PubMed=21654344; DOI=10.1097/CMR.0b013e328343a1d6; PMCID=PMC3131461
Kerrington R. Molhoek, Amber L. Shada, Mark Smolkin, Sudhir Chowbina, Jason Papin, David L. Brautigan, Craig L. Slingluff Jr.;
Comprehensive analysis of receptor tyrosine kinase activation in human melanomas reveals autocrine signaling through IGF-1R.
Melanoma Res. 21:274-284(2011)

PubMed=26405815; DOI=10.1371/journal.pone.0138210; PMCID=PMC4583389
Brian J. Capaldo, Devin Grimm Roller, Mark J. Axelrod, Alexander F. Koeppel, Emanuel F. Petricoin 3rd, Craig L. Slingluff Jr., Michael J. Weber, Aaron J. Mackey, Daniel Gioeli, Stefan Bekiranov;
Systems analysis of adaptive responses to MAP kinase pathway blockade in BRAF mutant melanoma.
PLoS ONE 10:e0138210.1-e0138210.25(2015)

PubMed=26673621; DOI=10.18632/oncotarget.6548; PMCID=PMC4823068
Devin Grimm Roller, Brian J. Capaldo, Stefan Bekiranov, Aaron J. Mackey, Mark Robert Conaway, Emanuel F. Petricoin 3rd, Daniel Gioeli, Michael J. Weber;
Combinatorial drug screening and molecular profiling reveal diverse mechanisms of intrinsic and adaptive resistance to BRAF inhibition in V600E BRAF mutant melanomas.
Oncotarget 7:2734-2753(2016)

Cross-references
Cell line collections (Providers) ATCC; CRL-3227
Cell line databases/resources cancercelllines; CVCL_A736
Encyclopedic resources Wikidata; Q54993234
Gene expression databases GEO; GSM1672070
GEO; GSM1672077
GEO; GSM1672090
GEO; GSM1672106
GEO; GSM1672122
GEO; GSM1672127
Entry history
Entry creation06-Jun-2012
Last entry update10-Apr-2025
Version number20