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Cellosaurus VMM12 (CVCL_A734)

[Text version]
Cell line name VMM12
Accession CVCL_A734
Resource Identification Initiative To cite this cell line use: VMM12 (RRID:CVCL_A734)
Comments Omics: Genomics; Whole exome sequencing.
Omics: Transcriptomics; Microarray.
Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000029.
Sequence variations
HLA typing Source: PubMed=10752474
Class I
HLA-AA*01,03
HLA-BB*07,14
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_F863 ! VMM12-EBV
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=10752474; DOI=10.1007/s002620050015; PMCID=PMC11037162
Craig L. Slingluff Jr., Teresa A. Colella, Lee Thompson, D. David Graham, Jonathan C.A. Skipper, Jennifer Caldwell, Larry Brinckerhoff, David J. Kittlesen, Donna H. Deacon, Correen Oei, Nancy L. Harthun ...Show all 15 authors... , Eric L. Huczko, Donald Frederick Hunt, Timothy L. Darrow, Victor H. Engelhard; Show fewer authors
Melanomas with concordant loss of multiple melanocytic differentiation proteins: immune escape that may be overcome by targeting unique or undefined antigens.
Cancer Immunol. Immunother. 48:661-672(2000)

PubMed=14871852; DOI=10.1158/0008-5472.CAN-03-2209
Kevin T. Hogan, Michael A. Coppola, Christine L. Gatlin, Lee W. Thompson, Jeffrey Shabanowitz, Donald Frederick Hunt, Victor H. Engelhard, Mark M. Ross, Craig L. Slingluff Jr.;
Identification of novel and widely expressed cancer/testis gene isoforms that elicit spontaneous cytotoxic T-lymphocyte reactivity to melanoma.
Cancer Res. 64:1157-1163(2004)

PubMed=15378283; DOI=10.1007/s00262-004-0592-y; PMCID=PMC11032761
Kevin T. Hogan, Jennifer N. Sutton, Kyo U. Chu, Jennifer A. Caldwell-Busby, Jeffrey Shabanowitz, Donald Frederick Hunt, Craig L. Slingluff Jr.;
Use of selected reaction monitoring mass spectrometry for the detection of specific MHC class I peptide antigens on A3 supertype family members.
Cancer Immunol. Immunother. 54:359-371(2005)

PubMed=20856146; DOI=10.1097/CMR.0b013e32833fafb4; PMCID=PMC3229868
Leann M. Mikesh, Manish Kumar, Gulsun Erdag, Kevin T. Hogan, Kerrington R. Molhoek, Marty W. Mayo, Craig L. Slingluff Jr.;
Evaluation of molecular markers of mesenchymal phenotype in melanoma.
Melanoma Res. 20:485-495(2010)

PubMed=26405815; DOI=10.1371/journal.pone.0138210; PMCID=PMC4583389
Brian J. Capaldo, Devin Grimm Roller, Mark J. Axelrod, Alexander F. Koeppel, Emanuel F. Petricoin 3rd, Craig L. Slingluff Jr., Michael J. Weber, Aaron J. Mackey, Daniel Gioeli, Stefan Bekiranov;
Systems analysis of adaptive responses to MAP kinase pathway blockade in BRAF mutant melanoma.
PLoS ONE 10:e0138210.1-e0138210.25(2015)

PubMed=26673621; DOI=10.18632/oncotarget.6548; PMCID=PMC4823068
Devin Grimm Roller, Brian J. Capaldo, Stefan Bekiranov, Aaron J. Mackey, Mark Robert Conaway, Emanuel F. Petricoin 3rd, Daniel Gioeli, Michael J. Weber;
Combinatorial drug screening and molecular profiling reveal diverse mechanisms of intrinsic and adaptive resistance to BRAF inhibition in V600E BRAF mutant melanomas.
Oncotarget 7:2734-2753(2016)

Cross-references
Cell line databases/resources cancercelllines; CVCL_A734
Encyclopedic resources Wikidata; Q54993228
Gene expression databases GEO; GSM1672073
GEO; GSM1672085
GEO; GSM1672092
GEO; GSM1672110
GEO; GSM1672120
GEO; GSM1672134
Polymorphism and mutation databases Cosmic; 890887
Entry history
Entry creation06-Jun-2012
Last entry update10-Apr-2025
Version number19