Cellosaurus cell line UKRV-Mel-16 (CVCL

Cellosaurus UKRV-Mel-16 (CVCL_A715)

[Text version]

Cell line name

UKRV-Mel-16

Synonyms

UKRV-Mel-16a

Accession

CVCL_A715

Resource Identification Initiative

To cite this cell line use: UKRV-Mel-16 (RRID:CVCL_A715)

Comments

Derived from site: Metastatic; Hypodermis; UBERON=UBERON_0002072.
Derived from site: Metastatic; Skin; UBERON=UBERON_0002097.

Sequence variations

Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (PubMed=17311103; PubMed=23348503).
Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (PubMed=23348503).

Disease

Melanoma (NCIt: C3224)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Sex of cell

Male

Age at sampling

24Y

Category

Cancer cell line

STR profile

Source(s): ESTDAB=ESTDAB-180

Markers:

Amelogenin	X
CSF1PO	11,12
D3S1358	16
D5S818	9,12
D7S820	8
D13S317	13
FGA	26
TH01	6,9.3
TPOX	8
vWA	17,20

Publications

PubMed=17311103; DOI=10.1371/journal.pone.0000236; PMCID=PMC1794595
Selma Ugurel, Ranjit K. Thirumaran, Sandra Bloethner, Andreas Gast, Antje Sucker, Jan Mueller-Berghaus, Werner Rittgen, Kari Hemminki, Jurgen C. Becker, Rajiv Kumar, Dirk Schadendorf;
B-RAF and N-RAS mutations are preserved during short time in vitro propagation and differentially impact prognosis.
PLoS ONE 2:e236.1-e236.13(2007)

PubMed=23348503; DOI=10.1126/science.1230062
Susanne Horn, Adina Figl, P. Sivaramakrishna Rachakonda, Christine Fischer, Antje Sucker, Andreas Gast, Stephanie Kadel, Iris Moll, Eduardo Nagore, Kari Hemminki, Dirk Schadendorf, Rajiv Kumar;
TERT promoter mutations in familial and sporadic melanoma.
Science 339:959-961(2013)

Cross-references

Cell line databases/resources

cancercelllines; CVCL_A715
ESTDAB; ESTDAB-180

Encyclopedic resources

Wikidata; Q54990599

Polymorphism and mutation databases

Cosmic; 2686518

Entry history

Entry creation

06-Jun-2012

Last entry update

19-Dec-2024

Version number