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Cellosaurus UKRV-Mel-15d (CVCL_A714)

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Cell line name UKRV-Mel-15d
Accession CVCL_A714
Resource Identification Initiative To cite this cell line use: UKRV-Mel-15d (RRID:CVCL_A714)
Sequence variations
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Arg (c.182A>G); ClinVar=VCV000013900; Zygosity=Unspecified (PubMed=23348503).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-146C>T (c.250C>T) (C250T); Zygosity=Unspecified; Note=In promoter (PubMed=23348503).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-149C>T (c.253C>T) (C253T); Zygosity=Unspecified; Note=In promoter (PubMed=23348503).
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_A713 ! UKRV-Mel-15a
CVCL_C397 ! UKRV-Mel-15b
CVCL_C398 ! UKRV-Mel-15c
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): ESTDAB=ESTDAB-229

Markers:
AmelogeninX
CSF1PO11
D3S135815,16
D5S81811
D7S8208,12
D13S31711,12
FGA21,22
TH016
TPOX8,12
vWA15,17

Run an STR similarity search on this cell line
Publications

PubMed=15760917; DOI=10.1093/carcin/bgi066
Sandra Bloethner, Bo-Wang Chen, Kari Hemminki, Jan Mueller-Berghaus, Selma Ugurel, Dirk Schadendorf, Rajiv Kumar;
Effect of common B-RAF and N-RAS mutations on global gene expression in melanoma cell lines.
Carcinogenesis 26:1224-1232(2005)

PubMed=23348503; DOI=10.1126/science.1230062
Susanne Horn, Adina Figl, P. Sivaramakrishna Rachakonda, Christine Fischer, Antje Sucker, Andreas Gast, Stephanie Kadel, Iris Moll, Eduardo Nagore, Kari Hemminki, Dirk Schadendorf, Rajiv Kumar;
TERT promoter mutations in familial and sporadic melanoma.
Science 339:959-961(2013)

Cross-references
Cell line databases/resources cancercelllines; CVCL_A714
ESTDAB; ESTDAB-229
Encyclopedic resources Wikidata; Q54990598
Polymorphism and mutation databases Cosmic; 906463
Cosmic; 1846704
Cosmic; 2686517
Entry history
Entry creation06-Jun-2012
Last entry update14-Aug-2025
Version number18