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Cellosaurus UKRV-Mel-15d (CVCL_A714)

[Text version]
Cell line name UKRV-Mel-15d
Accession CVCL_A714
Resource Identification Initiative To cite this cell line use: UKRV-Mel-15d (RRID:CVCL_A714)
Sequence variations
  • Mutation; HGNC; 7989; NRAS; Simple; p.Gln61Arg (c.182A>G); ClinVar=VCV000013900; Zygosity=Unspecified (PubMed=23348503).
  • Mutation; HGNC; 11730; TERT; Simple; c.1-146C>T (c.250C>T) (C250T); Zygosity=Unspecified; Note=In promoter (PubMed=23348503).
  • Mutation; HGNC; 11730; TERT; Simple; c.1-149C>T (c.253C>T) (C253T); Zygosity=Unspecified; Note=In promoter (PubMed=23348503).
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_A713 ! UKRV-Mel-15a
CVCL_C397 ! UKRV-Mel-15b
CVCL_C398 ! UKRV-Mel-15c
Category Cancer cell line
STR profile Source(s): ESTDAB=ESTDAB-229

Markers:
AmelogeninX
CSF1PO11
D3S135815,16
D5S81811
D7S8208,12
D13S31711,12
FGA21,22
TH016
TPOX8,12
vWA15,17

Run an STR similarity search on this cell line
Publications

PubMed=15760917; DOI=10.1093/carcin/bgi066
Bloethner S., Chen B.-W., Hemminki K., Muller-Berghaus J., Ugurel S., Schadendorf D., Kumar R.
Effect of common B-RAF and N-RAS mutations on global gene expression in melanoma cell lines.
Carcinogenesis 26:1224-1232(2005)

PubMed=23348503; DOI=10.1126/science.1230062
Horn S., Figl A., Rachakonda P.S., Fischer C., Sucker A., Gast A., Kadel S., Moll I., Nagore E., Hemminki K., Schadendorf D., Kumar R.
TERT promoter mutations in familial and sporadic melanoma.
Science 339:959-961(2013)

Cross-references
Cell line databases/resources cancercelllines; CVCL_A714
ESTDAB; ESTDAB-229
Encyclopedic resources Wikidata; Q54990598
Polymorphism and mutation databases Cosmic; 906463
Cosmic; 1846704
Cosmic; 2686517
Entry history
Entry creation06-Jun-2012
Last entry update02-May-2024
Version number16