Cellosaurus cell line UKRV-Mel-14a (CVCL

Cellosaurus UKRV-Mel-14a (CVCL_A710)

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Cell line name

UKRV-Mel-14a

Accession

CVCL_A710

Resource Identification Initiative

To cite this cell line use: UKRV-Mel-14a (RRID:CVCL_A710)

Sequence variations

Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (PubMed=23851445).
Mutation; HGNC; HGNC:1787; CDKN2A; Simple; p.Ala148Thr (c.442G>A); ClinVar=VCV000041580; Zygosity=Unspecified (PubMed=23851445).
Mutation; HGNC; HGNC:11998; TP53; Simple; p.Glu326fs (c.976insGA); Zygosity=Unspecified (PubMed=23851445).

Disease

Melanoma (NCIt: C3224)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Originate from same individual

CVCL_A711 ! UKRV-Mel-14b
CVCL_C409 ! UKRV-Mel-14c

Sex of cell

Female

Age at sampling

52Y

Category

Cancer cell line

STR profile

Source(s): ESTDAB=ESTDAB-110

Markers:

Amelogenin	X
CSF1PO	12
D3S1358	15,16
D5S818	11,12
D7S820	8,10
D13S317	10,12
FGA	25
TH01	7,9
TPOX	8,9
vWA	15,17

Publications

PubMed=19340423; DOI=10.1007/s00262-009-0701-z; PMCID=PMC11030131
Rosa Mendez, Natalia Aptsiauri, Ana Del Campo, Isabel Maleno, Teresa Cabrera, Francisco Ruiz-Cabello Osuna, Federico Garrido, Angel Garcia-Lora;
HLA and melanoma: multiple alterations in HLA class I and II expression in human melanoma cell lines from ESTDAB cell bank.
Cancer Immunol. Immunother. 58:1507-1515(2009)

PubMed=23851445; DOI=10.1158/1541-7786.MCR-13-0006
Christina Dahl, Claus Christensen, Goran Jonsson, Anders Lorentzen, Mette Louise Skjodt, Ake Borg, Graham Pawelec, Per Guldberg;
Mutual exclusivity analysis of genetic and epigenetic drivers in melanoma identifies a link between p14 ARF and RARbeta signaling.
Mol. Cancer Res. 11:1166-1178(2013)

Cross-references

Cell line databases/resources

cancercelllines; CVCL_A710
ESTDAB; ESTDAB-110

Encyclopedic resources

Wikidata; Q54990571

Polymorphism and mutation databases

Cosmic; 2163822

Entry history

Entry creation

06-Jun-2012

Last entry update

19-Dec-2024

Version number