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Cellosaurus UKRV-Mel-05 (CVCL_A703)

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Cell line name UKRV-Mel-05
Synonyms UKRV-Mel-5
Accession CVCL_A703
Resource Identification Initiative To cite this cell line use: UKRV-Mel-05 (RRID:CVCL_A703)
Sequence variations
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-146C>T (c.250C>T) (C250T); Zygosity=Unspecified; Note=In promoter (PubMed=23348503).
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): ESTDAB=ESTDAB-145

Markers:
AmelogeninX
CSF1PO12
D3S135816,17
D5S8189
D7S82010
D13S31711
FGA21
TH016,9
TPOX8
vWA14,17

Run an STR similarity search on this cell line
Publications

PubMed=15760917; DOI=10.1093/carcin/bgi066
Sandra Bloethner, Bo-Wang Chen, Kari Hemminki, Jan Mueller-Berghaus, Selma Ugurel, Dirk Schadendorf, Rajiv Kumar;
Effect of common B-RAF and N-RAS mutations on global gene expression in melanoma cell lines.
Carcinogenesis 26:1224-1232(2005)

PubMed=23348503; DOI=10.1126/science.1230062
Susanne Horn, Adina Figl, P. Sivaramakrishna Rachakonda, Christine Fischer, Antje Sucker, Andreas Gast, Stephanie Kadel, Iris Moll, Eduardo Nagore, Kari Hemminki, Dirk Schadendorf, Rajiv Kumar;
TERT promoter mutations in familial and sporadic melanoma.
Science 339:959-961(2013)

Cross-references
Cell line databases/resources ESTDAB; ESTDAB-145
Encyclopedic resources Wikidata; Q54990560
Polymorphism and mutation databases Cosmic; 906468
Cosmic; 1846692
Cosmic; 2686504
Entry history
Entry creation06-Jun-2012
Last entry update14-Aug-2025
Version number15