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Cellosaurus AQP4(E5415A-1H6-68) (CVCL_A6YZ)

[Text version]
Cell line name AQP4(E5415A-1H6-68)
Synonyms E5415A-1H6-68; E5415A
Accession CVCL_A6YZ
Resource Identification Initiative To cite this cell line use: AQP4(E5415A-1H6-68) (RRID:CVCL_A6YZ)
Comments Monoclonal antibody isotype: IgG2a, kappa.
Monoclonal antibody target: UniProtKB; P55088; Mouse Aqp4 (Note=Isoform M23).
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Hierarchy Parent: CVCL_2155 (P3/NS1/1-Ag4.1)
Category Hybridoma
Publications

PubMed=26637322; DOI=10.1186/s40478-015-0259-2; PMCID=PMC4670539
Kazuhiro Kurosawa, Tatsuro Misu, Yoshiki Takai, Douglas Kazutoshi Sato, Toshiyuki Takahashi, Yoichiro Abe, Hiroko Iwanari, Ryo Ogawa, Ichiro Nakashima, Kazuo Fujihara, Takao Hamakubo ...Show all 13 authors... , Masato Yasui, Masashi Aoki; Show fewer authors
Severely exacerbated neuromyelitis optica rat model with extensive astrocytopathy by high affinity anti-aquaporin-4 monoclonal antibody.
Acta Neuropathol. Commun. 3:82.1-82.15(2015)

PubMed=28955892; DOI=10.1016/j.bbrep.2016.05.017; PMCID=PMC5613303
Ping Huang, Yoshiki Takai, Osamu Kusano-Arai, Julia Ramadhanti, Hiroko Iwanari, Takayuki Miyauchi, Toshiko Sakihama, Jing-Yan Han, Masashi Aoki, Takao Hamakubo, Kazuo Fujihara ...Show all 13 authors... , Masato Yasui, Yoichiro Abe; Show fewer authors
The binding property of a monoclonal antibody against the extracellular domains of aquaporin-4 directs aquaporin-4 toward endocytosis.
Biochem. Biophys. Rep. 7:77-83(2016)

Cross-references
Cell line collections (Providers) RCB; RCB4883
Encyclopedic resources Wikidata; Q107113371
Entry history
Entry creation20-May-2021
Last entry update10-Sep-2024
Version number5