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Cellosaurus NP-2/CD4/FPRL1 (CVCL_A6US)

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Cell line name NP-2/CD4/FPRL1
Synonyms NP-2/CD4/EcoVR/FPRL1
Accession CVCL_A6US
Resource Identification Initiative To cite this cell line use: NP-2/CD4/FPRL1 (RRID:CVCL_A6US)
Comments Population: Japanese.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:1678; CD4.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:3827; FPR2.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Derived from site: In situ; Brain, left frontal lobe; UBERON=UBERON_0002811.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Met237Ile (c.711G>T); ClinVar=VCV000634770; Zygosity=Unspecified (from parent cell line).
Disease Glioblastoma (NCIt: C3058)
Glioblastoma (ORDO: Orphanet_360)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1R18 (NP-2/CD4)
Sex of cell Male
Age at sampling 63Y
Category Cancer cell line
Publications

PubMed=18577234; DOI=10.1186/1742-4690-5-52; PMCID=PMC2453146
Nobuaki Shimizu, Atsushi Tanaka, Takahisa Mori, Takahiro Ohtsuki, Aliful Hoque, Atsushi Jinno-Oue, Chatchawann Apichartpiyakul, Shigeru Kusagawa, Yutaka Takebe, Hiroo Hoshino;
A formylpeptide receptor, FPRL1, acts as an efficient coreceptor for primary isolates of human immunodeficiency virus.
Retrovirology 5:52.1-52.14(2008)

Cross-references
Cell line collections (Providers) RCB; RCB5311
Cell line databases/resources cancercelllines; CVCL_A6US
Encyclopedic resources Wikidata; Q107116576
Entry history
Entry creation20-May-2021
Last entry update14-Aug-2025
Version number9