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Cellosaurus ED-70423C(-) (CVCL_A6TW)

[Text version]
Cell line name ED-70423C(-)
Synonyms ED-70423CB(-)
Accession CVCL_A6TW
Resource Identification Initiative To cite this cell line use: ED-70423C(-) (RRID:CVCL_A6TW)
Comments Population: Japanese.
Characteristics: Lost its original IL2 dependency.
Transformant: NCBI_TaxID; 11908; Human T-lymphotropic virus 1 (HTLV-1).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Cell type: T-cell; CL=CL_0000084.
Disease Adult T-cell leukemia/lymphoma (NCIt: C3184)
Adult T-cell leukemia/lymphoma (ORDO: Orphanet_86875)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_A6SJ (ED-70423C)
Sex of cell Male
Age at sampling 34Y
Category Cancer cell line
Publications

PubMed=32210945; DOI=10.3389/fmicb.2020.00356; PMCID=PMC7067701
Maeda M., Tanabe-Shibuya J., Miyazato P., Masutani H., Yasunaga J.-i., Usami K., Shimizu A., Matsuoka M.
IL-2/IL-2 receptor pathway plays a crucial role in the growth and malignant transformation of HTLV-1-infected T cells to develop adult T-cell leukemia.
Front. Microbiol. 11:356.1-356.17(2020)

Cross-references
Cell line collections (Providers) RCB; RCB3558
Encyclopedic resources Wikidata; Q107114855
Entry history
Entry creation20-May-2021
Last entry update29-Jun-2023
Version number6