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Cellosaurus ED-50823(-) (CVCL_A6TH)

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Cell line name ED-50823(-)
Accession CVCL_A6TH
Resource Identification Initiative To cite this cell line use: ED-50823(-) (RRID:CVCL_A6TH)
Comments Population: Japanese.
Characteristics: Lost its original IL2 dependency.
Transformant: NCBI_TaxID; 11908; Human T-lymphotropic virus 1 (HTLV-1).
Donor information: Established from a patient suffering from adult T-cell leukemia/lymphoma (ATLL).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_A6SK (ED-50823)
Sex of cell Male
Age at sampling 34Y
Category Transformed cell line
Publications

PubMed=32210945; DOI=10.3389/fmicb.2020.00356; PMCID=PMC7067701
Michiyuki Maeda, Junko Tanabe-Shibuya, Paola Miyazato, Hiroshi Masutani, Jun-ichirou Yasunaga, Kazumasa Usami, Akira Shimizu, Masao Matsuoka;
IL-2/IL-2 receptor pathway plays a crucial role in the growth and malignant transformation of HTLV-1-infected T cells to develop adult T-cell leukemia.
Front. Microbiol. 11:356.1-356.17(2020)

Cross-references
Cell line collections (Providers) RCB; RCB3540
Encyclopedic resources Wikidata; Q107114852
Entry history
Entry creation20-May-2021
Last entry update29-Jun-2023
Version number6