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Cellosaurus SNT-8 (CVCL_A677)

[Text version]
Cell line name SNT-8
Synonyms SNT8
Accession CVCL_A677
Resource Identification Initiative To cite this cell line use: SNT-8 (RRID:CVCL_A677)
Comments Population: Japanese.
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Omics: Transcriptomics; Microarray.
Omics: Variations; CNV analysis.
Derived from site: In situ; Nose, nasal cavity; UBERON=UBERON_0001707.
Disease Nasal type extranodal NK/T-cell lymphoma (NCIt: C4684)
Extranodal nasal NK/T cell lymphoma (ORDO: Orphanet_86879)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 48Y
Category Cancer cell line
Publications

PubMed=11157488; DOI=10.1182/blood.V97.3.708
Nagata H., Konno A., Kimura N., Zhang Y., Kimura M., Demachi A., Sekine T., Yamamoto K., Shimizu N.
Characterization of novel natural killer (NK)-cell and gammadelta T-cell lines established from primary lesions of nasal T/NK-cell lymphomas associated with the Epstein-Barr virus.
Blood 97:708-713(2001)

PubMed=12780797; DOI=10.1046/j.1365-2141.2003.04359.x
Zhang Y., Nagata H., Ikeuchi T., Mukai H., Oyoshi M.K., Demachi A., Morio T., Wakiguchi H., Kimura N., Shimizu N., Yamamoto K.
Common cytological and cytogenetic features of Epstein-Barr virus (EBV)-positive natural killer (NK) cells and cell lines derived from patients with nasal T/NK-cell lymphomas, chronic active EBV infection and hydroa vacciniforme-like eruptions.
Br. J. Haematol. 121:805-814(2003)

PubMed=16827800; DOI=10.1111/j.1349-7006.2006.00226.x; PMCID=PMC11159954
Liu A., Takakuwa T., Luo W.-J., Fujita S., Aozasa K.
Alterations in ATR in nasal NK/T-cell lymphoma and chronic active Epstein-Barr virus infection.
Cancer Sci. 97:605-610(2006)

PubMed=20132662; DOI=10.1179/102453310X12583347009450
Zhang Y., Ohyashiki J.H., Shimizu N., Ohyashiki K.
Aberrant expression of NK cell receptors in Epstein-Barr virus-positive gammadelta T-cell lymphoproliferative disorders.
Hematology 15:43-47(2010)

PubMed=21052088; DOI=10.1038/leu.2010.255
Iqbal J., Weisenburger D.D., Chowdhury A., Tsai M.-Y., Srivastava G., Greiner T.C., Kucuk C., Deffenbacher K.E., Vose J.M., Smith L., Au W.Y., Nakamura S., Seto M., Delabie J., Berger F., Loong F., Ko Y.-H., Sng I., Liu X., Loughran T.P. Jr., Armitage J.O., Chan W.-C.
International Peripheral T-cell Lymphoma Project
Natural killer cell lymphoma shares strikingly similar molecular features with a group of non-hepatosplenic gammadelta T-cell lymphoma and is highly sensitive to a novel aurora kinase A inhibitor in vitro.
Leukemia 25:348-358(2011)

PubMed=22102884; DOI=10.1371/journal.pone.0027271; PMCID=PMC3213120
Ramakrishnan R., Donahue H., Garcia D., Tan J., Shimizu N., Rice A.P., Ling P.D.
Epstein-Barr virus BART9 miRNA modulates LMP1 levels and affects growth rate of nasal NK T cell lymphomas.
PLoS ONE 6:e27271.1-e27271.12(2011)

PubMed=25586472; DOI=10.1038/ncomms7025; PMCID=PMC7743911
Kucuk C., Jiang B., Hu X.-Z., Zhang W.-Y., Chan J.K.C., Xiao W.-M., Lack N., Alkan C., Williams J.C., Avery K.N., Kavak P., Scuto A., Sen E., Gaulard P., Staudt L.M., Iqbal J., Zhang W.-W., Cornish A., Gong Q., Yang Q.-P., Sun H., d'Amore F.A., Leppa S., Liu W.-P., Fu K., de Leval L., McKeithan T.W., Chan W.-C.
Activating mutations of STAT5B and STAT3 in lymphomas derived from gammadelta-T or NK cells.
Nat. Commun. 6:6025.1-6025.12(2015)

Cross-references
Cell line databases/resources cancercelllines; CVCL_A677
Encyclopedic resources Wikidata; Q54955077
Gene expression databases GEO; GSM349850
GEO; GSM349851
GEO; GSM472009
GEO; GSM3021088
GEO; GSM3021089
Polymorphism and mutation databases Cosmic; 2390121
Progenetix; CVCL_A677
Entry history
Entry creation06-Jun-2012
Last entry update10-Apr-2025
Version number18