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Cellosaurus OHN-GM (CVCL_A662)

[Text version]
Cell line name OHN-GM
Synonyms OHNGM
Accession CVCL_A662
Resource Identification Initiative To cite this cell line use: OHN-GM (RRID:CVCL_A662)
Comments Population: Japanese.
Characteristics: CSF2 dependent.
Doubling time: ~60 hours (PubMed=9266938).
Omics: Variations; SNP array analysis.
Donor information: Originally the patient was suffering from Hodgkin lymphoma.
Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
Sequence variations
Disease Myelodysplastic syndrome (NCIt: C3247)
Therapy-related acute myeloid leukemia (NCIt: C8252)
Therapy related acute myeloid leukemia and myelodysplastic syndrome (ORDO: Orphanet_86846)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 60Y
Category Cancer cell line
Publications

PubMed=9266938; DOI=10.1046/j.1365-2141.1997.2413058.x
Masami Nagai, Mitsuhiro Fujita, Takashi Ikeda, Minoru Ohmori, Hiroko Kuwabara, Genji Yamaoka, Kimio Tanaka, Nanao Kamada, Masafumi Taniwaki, Tokiko Inoue, Shozo Irino, Jiro Takahara;
Alterations of p53 and Rb genes in a novel human GM-CSF-dependent myeloid cell line (OHN-GM) established from therapy-related leukaemia.
Br. J. Haematol. 98:392-398(1997)

DOI=10.1016/B978-0-12-221970-2.50457-5
Hans Gunther Drexler;
The leukemia-lymphoma cell line factsbook.
(In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001)

PubMed=27750403; DOI=10.1002/gcc.22430
Anna Palau, Mar Mallo, Laura Palomo, Ines Rodriguez-Hernandez, Jeannine Diesch, Diana Campos, Isabel Granada, Jordi Junca, Hans Gunther Drexler, Francesc Sole, Marcus Buschbeck;
Immunophenotypic, cytogenetic, and mutational characterization of cell lines derived from myelodysplastic syndrome patients after progression to acute myeloid leukemia.
Genes Chromosomes Cancer 56:243-252(2017)

PubMed=29533902; DOI=10.1515/hsz-2017-0321
Hans Gunther Drexler, Claudia Pommerenke, Sonja Eberth, Stefan Nagel;
Hodgkin lymphoma cell lines: to separate the wheat from the chaff.
Biol. Chem. 399:511-523(2018)

Cross-references
Cell line databases/resources cancercelllines; CVCL_A662
Encyclopedic resources Wikidata; Q54931895
Gene expression databases GEO; GSM2124119
Polymorphism and mutation databases Cosmic; 787473
Cosmic; 975295
Cosmic; 1281350
Progenetix; CVCL_A662
Entry history
Entry creation06-Jun-2012
Last entry update10-Apr-2025
Version number18