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Cellosaurus INT-MEL-12 (CVCL_A648)

[Text version]
Cell line name INT-MEL-12
Synonyms Me10538; ME10538; ME 10538; Me 10538; Me1053/8; 10538
Accession CVCL_A648
Resource Identification Initiative To cite this cell line use: INT-MEL-12 (RRID:CVCL_A648)
Comments Misspelling: ME10358; Note=Occasionally.
Sequence variations
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_C690 ! LCL10538
Sex of cell Female
Age at sampling 56Y
Category Cancer cell line
Publications

PubMed=2469723; DOI=10.4049/jimmunol.142.10.3692
Andrea Anichini, Arabella Mazzocchi, Giuseppe Fossati, Giorgio Parmiani;
Cytotoxic T lymphocyte clones from peripheral blood and from tumor site detect intratumor heterogeneity of melanoma cells. Analysis of specificity and mechanisms of interaction.
J. Immunol. 142:3692-3701(1989)

PubMed=2776368; DOI=10.1007/BF01753674
Lidia Larizza, Luisa Doneda, Monica Rodolfo, Giuseppe Fossati;
High incidence of chromosomal lesions involving C-heterochromatin in four human melanoma lines.
Clin. Exp. Metastasis 7:633-644(1989)

PubMed=8459226; DOI=10.1084/jem.177.4.989; PMCID=PMC2190978
Andrea Anichini, Cristina Maccalli, Roberta Mortarini, Stefania Salvi, Arabella Mazzocchi, Paola Squarcina, Meenhard Herlyn, Giorgio Parmiani;
Melanoma cells and normal melanocytes share antigens recognized by HLA-A2-restricted cytotoxic T cell clones from melanoma patients.
J. Exp. Med. 177:989-998(1993)

PubMed=7520026; DOI=10.1002/ijc.2910580413
Peter Hersey, Zhao-Yi Si, Melanie J. Smith, Wayne D. Thomas;
Expression of the co-stimulatory molecule B7 on melanoma cells.
Int. J. Cancer 58:527-532(1994)

PubMed=8980186; DOI=10.1002/(SICI)1097-0215(19961211)68:6<795::AID-IJC18>3.0.CO;2-#
Wayne D. Thomas, Melanie J. Smith, Zhao-Yi Si, Peter Hersey;
Expression of the co-stimulatory molecule CD40 on melanoma cells.
Int. J. Cancer 68:795-801(1996)

PubMed=9354451
Marina Castellano, Pamela M. Pollock, Marilyn K. Walters, Louise E. Sparrow, Louise M. Down, Brian G. Gabrielli, Peter G. Parsons, Nicholas K. Hayward;
CDKN2A/p16 is inactivated in most melanoma cell lines.
Cancer Res. 57:4868-4875(1997)

PubMed=9725211; DOI=10.4049/jimmunol.161.5.2195
Wayne D. Thomas, Peter Hersey;
TNF-related apoptosis-inducing ligand (TRAIL) induces apoptosis in Fas ligand-resistant melanoma cells and mediates CD4 T cell killing of target cells.
J. Immunol. 161:2195-2200(1998)

DOI=10.1007/0-306-46872-7_16
Andrea Anichini, Roberta Mortarini, Claudia Vegetti, Alessandra Molla, Alessandra Borri, Giorgio Parmiani;
Melanoma: the Milan melanoma cell lines.
(In book chapter) Human cell culture. Vol. 1. Cancer cell lines part 1; Masters, John R.W. & Palsson, Bernhard Orn (eds.); pp.283-292; Kluwer Academic Publishers; New York; USA (1999)

PubMed=9973437; DOI=10.4049/jimmunol.162.3.1739
Chiara Castelli, Paolo Tarsini, Arabella Mazzocchi, Francesca Rini, Licia Rivoltini, Fernando Ravagnani, Francesco Gallino, Filiberto Belli, Giorgio Parmiani;
Novel HLA-Cw8-restricted T cell epitopes derived from tyrosinase-related protein-2 and gp100 melanoma antigens.
J. Immunol. 162:1739-1748(1999)

PubMed=15048078; DOI=10.1038/sj.onc.1207563
Sandra Pavey, Peter Johansson, Leisl Packer, Jennifer Taylor, Mitchell S. Stark, Pamela M. Pollock, Graeme J. Walker, Glen M. Boyle, Ursula Harper, Sarah-Jane Cozzi, Katherine Hansen ...Show all 20 authors... , Laura Yudt, Chris Schmidt, Peter Hersey, Kay Adrian Oswald Ellem, Michael G.E. O'Rourke, Peter G. Parsons, Paul S. Meltzer, Markus Ringner, Nicholas K. Hayward; Show fewer authors
Microarray expression profiling in melanoma reveals a BRAF mutation signature.
Oncogene 23:4060-4067(2004)

PubMed=22383533; DOI=10.1158/1535-7163.MCT-11-0676
Ken Dutton-Regester, Darryl Irwin, Priscilla Hunt, Lauren G. Aoude, Varsha Tembe, Gulietta M. Pupo, Cathy Lanagan, Candace D. Carter, Linda O'Connor, Michael O'Rourke, Richard Anthony Scolyer ...Show all 15 authors... , Graham J. Mann, Christopher W. Schmidt, Adrian Herington, Nicholas K. Hayward; Show fewer authors
A high-throughput panel for identifying clinically relevant mutation profiles in melanoma.
Mol. Cancer Ther. 11:888-897(2012)

PubMed=25576923; DOI=10.18632/oncotarget.2995; PMCID=PMC4413617
Rossella Loria, Giulia Bon, Valentina Perotti, Enzo Gallo, Ilaria Bersani, Paola Baldassari, Manuela Porru, Carlo Leonetti, Selene Di Carlo, Paolo Visca, Maria Felice Brizzi ...Show all 14 authors... , Andrea Anichini, Roberta Mortarini, Rita Falcioni; Show fewer authors
Sema6A and Mical1 control cell growth and survival of BRAFV600E human melanoma cells.
Oncotarget 6:2779-2793(2015)

Cross-references
Cell line databases/resources cancercelllines; CVCL_A648
Encyclopedic resources Wikidata; Q54897757
Gene expression databases GEO; GSM1403082
GEO; GSM1403083
GEO; GSM1403084
Polymorphism and mutation databases Cosmic; 889006
Cosmic; 928710
Cosmic; 1211153
Entry history
Entry creation06-Jun-2012
Last entry update19-Dec-2024
Version number19