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Cellosaurus KMO-90 (CVCL_A636)

[Text version]
Cell line name KMO-90
Accession CVCL_A636
Resource Identification Initiative To cite this cell line use: KMO-90 (RRID:CVCL_A636)
Comments Population: Japanese.
Doubling time: ~72 hours (PubMed=8412323).
Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
Sequence variations
Disease Childhood B acute lymphoblastic leukemia (NCIt: C9140)
B acute lymphoblastic leukemia with t(1;19)(q23;p13.3) E2A-PBX1 (TCF3-PBX1) (NCIt: C80347)
B-lymphoblastic leukemia/lymphoma with t(1;19)(q23;p13.3) (ORDO: Orphanet_585956)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_QW97 ! KMO-R
Sex of cell Female
Age at sampling 12Y
Category Cancer cell line
Publications

PubMed=8372807; DOI=10.1002/ajh.2830430404
Manabu Sotomatsu, Shin-ichiro Yugami, Toshiji Shitara, Takayoshi Kuroume;
Dipyridamole enhancement of drug sensitivity in acute lymphoblastic leukemia cells.
Am. J. Hematol. 43:251-255(1993)

PubMed=8412323
Manabu Sotomatsu, Yasuhide Hayashi, Machiko Kawamura, Shin-ichiro Yugami, Toshiji Shitara;
Establishment of a new human pre-B acute lymphoblastic leukemia cell line (KMO-90) with 1;19 translocation carrying p53 gene alterations.
Leukemia 7:1615-1620(1993)

PubMed=7727782; DOI=10.1182/blood.V85.9.2546.bloodjournal8592546
Machiko Kawamura, Akira Kikuchi, Shigetoshi Kobayashi, Ryoji Hanada, Keiko Yamamoto, Keizou Horibe, Takaaki Shikano, Kazuhiro Ueda, Kenshi Hayashi, Takao Sekiya, Yasuhide Hayashi;
Mutations of the p53 and ras genes in childhood t(1;19)-acute lymphoblastic leukemia.
Blood 85:2546-2552(1995)

PubMed=10637496; DOI=10.1038/sj.leu.2401604
Hans Gunther Drexler, Severine Fombonne, Yoshinobu Matsuo, Z.-B. Hu, Hiroyuki Hamaguchi, Cord C. Uphoff;
p53 alterations in human leukemia-lymphoma cell lines: in vitro artifact or prerequisite for cell immortalization?
Leukemia 14:198-206(2000)

DOI=10.1016/B978-0-12-221970-2.50457-5
Hans Gunther Drexler;
The leukemia-lymphoma cell line factsbook.
(In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001)

Cross-references
Cell line databases/resources cancercelllines; CVCL_A636
Encyclopedic resources Wikidata; Q54900128
Polymorphism and mutation databases Cosmic; 710458
IARC_TP53; 962
IARC_TP53; 3944
Entry history
Entry creation06-Jun-2012
Last entry update19-Dec-2024
Version number18