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Cellosaurus JD38 (CVCL_A631)

[Text version]
Cell line name JD38
Synonyms JD 38
Accession CVCL_A631
Resource Identification Initiative To cite this cell line use: JD38 (RRID:CVCL_A631)
Comments Virology: EBV-negative.
Doubling time: 26 hours (PubMed=8402660).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Cell type: B-cell; CL=CL_0000236.
Sequence variations
Disease B-cell non-Hodgkin lymphoma (NCIt: C3457)
B-cell non-Hodgkin lymphoma (ORDO: Orphanet_171915)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Category Cancer cell line
Publications

PubMed=6286763; DOI=10.4049/jimmunol.129.3.1336
David Benjamin, Ian Trevor Magrath, Robert T. Maguire, Carol Janus, Heather D. Todd-Kulikowsk, Robert G. Parsons;
Immunoglobulin secretion by cell lines derived from African and American undifferentiated lymphomas of Burkitt's and non-Burkitt's type.
J. Immunol. 129:1336-1342(1982)

PubMed=3921823; DOI=10.1128/mcb.5.3.501-509.1985; PMCID=PMC366742
Louise C. Showe, Marion Ballantine, Kazuko Nishikura, Jan Erikson, Hideko Kaji, Carlo Maria Croce;
Cloning and sequencing of a c-myc oncogene in a Burkitt's lymphoma cell line that is translocated to a germ line alpha switch region.
Mol. Cell. Biol. 5:501-509(1985)

PubMed=3100061; DOI=10.1016/0008-8749(86)90099-7
David Benjamin, Leonard S. Bazar, Brett Wallace, Robert J. Jacobson;
Heterogeneity of B-cell growth factor receptor reactivity in healthy donors and in patients with chronic lymphatic leukemia: relationship to B-cell-derived lymphokines.
Cell. Immunol. 103:394-408(1986)

PubMed=2052620; DOI=10.1073/pnas.88.12.5413; PMCID=PMC51883
Gianluca Gaidano, Paola Ballerini, Jerry Z. Gong, Giorgio Inghirami, Antonino Neri, Elizabeth W. Newcomb, Ian Trevor Magrath, Daniel M. Knowles, Riccardo Dalla-Favera;
p53 mutations in human lymphoid malignancies: association with Burkitt lymphoma and chronic lymphocytic leukemia.
Proc. Natl. Acad. Sci. U.S.A. 88:5413-5417(1991)

PubMed=1325212; DOI=10.1182/blood.V80.5.1289.1289
David Benjamin, Thomas J. Knobloch, Mark A. Dayton;
Human B-cell interleukin-10: B-cell lines derived from patients with acquired immunodeficiency syndrome and Burkitt's lymphoma constitutively secrete large quantities of interleukin-10.
Blood 80:1289-1298(1992)

PubMed=8344493; DOI=10.1096/fasebj.7.10.8344493
Kishor G. Bhatia, Walter Goldschmidts, Marina I. Gutierrez, Gianluca Gaidano, Riccardo Dalla-Favera, Ian Trevor Magrath;
Hemi- or homozygosity: a requirement for some but not other p53 mutant proteins to accumulate and exert a pathogenetic effect.
FASEB J. 7:951-956(1993)

PubMed=8402660
Patrick M. O'Connor, Joany Jackman, Daniel Jondle, Kishor G. Bhatia, Ian Trevor Magrath, Kurt W. Kohn;
Role of the p53 tumor suppressor gene in cell cycle arrest and radiosensitivity of Burkitt's lymphoma cell lines.
Cancer Res. 53:4776-4780(1993)

PubMed=8176200; DOI=10.4049/jimmunol.152.10.4749
David Benjamin, Venkatanarayanan Sharma, Thomas J. Knobloch, Richard J. Armitage, Mark A. Dayton, Raymond G. Goodwin;
B cell IL-7. Human B cell lines constitutively secrete IL-7 and express IL-7 receptors.
J. Immunol. 152:4749-4757(1994)

PubMed=8568269; DOI=10.4049/jimmunol.156.4.1626
David Benjamin, Venkatanarayanan Sharma, Marek Kubin, Jared L. Klein, Alexandrina Sartori, Jane Holliday, Giorgio Trinchieri;
IL-12 expression in AIDS-related lymphoma B cell lines.
J. Immunol. 156:1626-1637(1996)

PubMed=9192833
Barry W. Cherney, Kishor G. Bhatia, Cecilia Sgadari, Marina I. Gutierrez, Howard S. Mostowski, Sandra E. Pike, Ghanshyam Gupta, Ian Trevor Magrath, Giovanna Tosato;
Role of the p53 tumor suppressor gene in the tumorigenicity of Burkitt's lymphoma cells.
Cancer Res. 57:2508-2515(1997)

PubMed=9473234; DOI=10.1182/blood.V91.5.1680
Ulf Klangby, Ismail Okan, Kristinn Petur Magnusson, Martin Wendland, Peter Lind, Klas G. Wiman;
p16/INK4a and p15/INK4b gene methylation and absence of p16/INK4a mRNA and protein expression in Burkitt's lymphoma.
Blood 91:1680-1687(1998)

PubMed=9563901
Sai-Jun Fan, Barry W. Cherney, William C. Reinhold, Kimberly Rucker, Patrick M. O'Connor;
Disruption of p53 function in immortalized human cells does not affect survival or apoptosis after taxol or vincristine treatment.
Clin. Cancer Res. 4:1047-1054(1998)

PubMed=9787181; DOI=10.1182/blood.V92.9.3410
Akira Sakai, Catherine Thieblemont, Axel Wellmann, Elaine Sarkin Jaffe, Mark Raffeld;
PTEN gene alterations in lymphoid neoplasms.
Blood 92:3410-3415(1998)

PubMed=9973220
Marina I. Gutierrez, Barry W. Cherney, Azhar Hussain, Howard S. Mostowski, Giovanna Tosato, Ian Trevor Magrath, Kishor G. Bhatia;
Bax is frequently compromised in Burkitt's lymphomas with irreversible resistance to Fas-induced apoptosis.
Cancer Res. 59:696-703(1999)

Cross-references
Cell line databases/resources cancercelllines; CVCL_A631
Encyclopedic resources Wikidata; Q54898546
Polymorphism and mutation databases Cosmic; 850209
Cosmic; 931124
IARC_TP53; 167
Entry history
Entry creation06-Jun-2012
Last entry update10-Apr-2025
Version number21