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Cellosaurus HOM-2 (CVCL_A612)

[Text version]
Cell line name HOM-2
Synonyms HOM 2; HOM2
Accession CVCL_A612
Resource Identification Initiative To cite this cell line use: HOM-2 (RRID:CVCL_A612)
Comments Part of: 10th International Histocompatibility Workshop (10IHW) cell line panel.
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Cell type: B-cell; CL=CL_0000236.
HLA typing Source: IPD-IMGT/HLA=10755
Class I
HLA-AA*03:01:01:01
HLA-BB*27:05:02
HLA-CC*01:02:01:06
Class II
HLA-DPDPA1*01
DPB1*04:01:01
HLA-DQDQA1*01:01
DQB1*05:01:01
HLA-DRDRA*01:01
DRB1*01:01:01
DRB6*01:01
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling Age unspecified
Category Transformed cell line
Publications

PubMed=158761; DOI=10.1073/pnas.76.7.3507; PMCID=PMC383856
Farrant J., Knight S.C.
Help and suppression by lymphoid cells as a function of cellular concentration.
Proc. Natl. Acad. Sci. U.S.A. 76:3507-3510(1979)

DOI=10.1007/978-1-4612-3552-1_2
Yang S.Y., Milford E.L., Hammerling U., Dupont B.
Description of the reference panel of B-lymphoblastoid cell lines for factors of the HLA system: the B-cell line panel designed for the Tenth International Histocompatibility Workshop.
(In book chapter) Immunobiology of HLA. Volume I. Histocompatibility testing 1987; Dupont B. (eds.); pp.11-19; Springer; New York; USA (1989)

DOI=10.1007/978-1-4612-3552-1_4
Mickelson E.M., Reinsmoen N.L., Robbins F.-M., Hartzman R.J., Odum N., Svejgaard A., Farrell C., Honeyman M.C., Flomenberg N., Sell T.W., Eckels D.D.
HLA-Dw and HLA-DP typing of the reference panel of B-lymphoblastoid cell lines.
(In book chapter) Immunobiology of HLA. Volume I. Histocompatibility testing 1987; Dupont B. (eds.); pp.38-42; Springer; New York; USA (1989)

DOI=10.1007/978-1-4612-3552-1_5
Yang S.Y.
Assignment of HLA-A and HLA-B antigens for the reference panel of B-lymphoblastoid cell lines determined by one-dimensional isoelectric focusing (lD-IEF) gel electrophoresis.
(In book chapter) Immunobiology of HLA. Volume I. Histocompatibility testing 1987; Dupont B. (eds.); pp.43-44; Springer; New York; USA (1989)

DOI=10.1007/978-1-4612-3552-1_6
Knowles R.W.
Assignment of HLA-class II alpha and beta chain 2-D gel patterns for the workshop reference panel of B-lymphoblastoid cell lines.
(In book chapter) Immunobiology of HLA. Volume I. Histocompatibility testing 1987; Dupont B. (eds.); pp.44-46; Springer; New York; USA (1989)

DOI=10.1007/978-1-4612-3552-1_7
Flomenberg N.
Assignment of T-cell-defined (TCD) HLA class II specificities for the reference panel of B-lymphoblastoid cell lines.
(In book chapter) Immunobiology of HLA. Volume I. Histocompatibility testing 1987; Dupont B. (eds.); pp.46-48; Springer; New York; USA (1989)

PubMed=7614994; DOI=10.1002/eji.1830250627
Wedderburn L.R., Searle S.J.M., Rees A.R., Lamb J.R., Owen M.J.
Mapping T cell recognition: the identification of a T cell receptor residue critical to the specific interaction with an influenza hemagglutinin peptide.
Eur. J. Immunol. 25:1654-1662(1995)

PubMed=8813743; DOI=10.1111/j.1399-0039.1996.tb02596.x
Prasad V.K., Yang S.Y.
Allele assignment for HLA-A, -B, and -C genes to the Tenth International Histocompatibility Workshop cell lines.
Tissue Antigens 47:538-546(1996)

PubMed=29171935; DOI=10.1111/tan.13184
Turner T.R., Hayhurst J.D., Hayward D.R., Bultitude W.P., Barker D.J., Robinson J., Madrigal J.A., Mayor N.P., Marsh S.G.E.
Single molecule real-time DNA sequencing of HLA genes at ultra-high resolution from 126 international HLA and immunogenetics workshop cell lines.
HLA 91:88-101(2018)

Cross-references
Cell line collections (Providers) ECACC; 98092902
Cell line databases/resources dbMHC; 48898
IHW; IHW09005
IPD-IMGT/HLA; 10755
Anatomy/cell type resources BTO; BTO:0003106
Encyclopedic resources Wikidata; Q54890143
Experimental variables resources EFO; EFO_0022657
Entry history
Entry creation06-Jun-2012
Last entry update10-Sep-2024
Version number21