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Cellosaurus HEL-P1 (CVCL_A5ZM)

[Text version]
Cell line name HEL-P1
Accession CVCL_A5ZM
Resource Identification Initiative To cite this cell line use: HEL-P1 (RRID:CVCL_A5ZM)
Comments Population: Caucasian.
Characteristics: Subline that highly expresses KIT and GYPA (PubMed=7538619).
Doubling time: 18.9 +- 1.4 hours (Note=In serum-containing medium), 23.6 +- 0.9 hours (Note=In serum-free medium) (PubMed=7538619).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Cell type: Erythroblast; CL=CL_0000765.
Sequence variations
  • Mutation; HGNC; HGNC:6192; JAK2; Simple; p.Val617Phe (c.1849G>T); ClinVar=VCV000014662; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Met133Lys (c.398T>A); ClinVar=VCV002430159; Zygosity=Homozygous (from parent cell line).
Disease Erythroleukemia (NCIt: C7152)
Acute erythroid leukemia (ORDO: Orphanet_318)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0001 (HEL)
Sex of cell Male
Age at sampling 30Y
Category Cancer cell line
Publications

PubMed=7538619; DOI=10.1016/0145-2126(94)00160-c
Akira Kubota, Seiichi Okamura, Kazuya Shimoda, Wataru Ikematsu, Teruhisa Otsuka, Yoshiyuki Niho;
Analysis of c-kit expression of human erythroleukemia cell line, HEL: clonal variation and relationship with erythroid and megakaryocytic phenotype.
Leuk. Res. 19:283-290(1995)

Cross-references
Cell line databases/resources cancercelllines; CVCL_A5ZM
Encyclopedic resources Wikidata; Q107115312
Entry history
Entry creation20-May-2021
Last entry update14-Aug-2025
Version number7