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Cellosaurus S2:DER2f (CVCL_A5UZ)

[Text version]
Cell line name S2:DER2f
Synonyms D2F; D2f; DER2-expressing S2 cells; D2R
Accession CVCL_A5UZ
Resource Identification Initiative To cite this cell line use: S2:DER2f (RRID:CVCL_A5UZ)
Comments Group: Insect cell line.
Transfected with: FlyBase_Gene; FBgn0000434; Der.
Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
Derived from site: In situ; Whole embryo; UBERON=UBERON_0000922.
Species of origin Drosophila melanogaster (Fruit fly) (NCBI Taxonomy: 7227)
Breed/subspecies: Oregon-R.
Hierarchy Parent: CVCL_Z232 (Schneider 2)
Sex of cell Male
Age at sampling Late embryonic stage
Category Spontaneously immortalized cell line

PubMed=7601354; DOI=10.1101/gad.9.12.1518
Schweitzer R., Shaharabany M., Seger R., Shilo B.-Z.
Secreted Spitz triggers the DER signaling pathway and is a limiting component in embryonic ventral ectoderm determination.
Genes Dev. 9:1518-1529(1995)

PubMed=15329724; DOI=10.1038/nature02840
Klein D.E., Nappi V.M., Reeves G.T., Shvartsman S.Y., Lemmon M.A.
Argos inhibits epidermal growth factor receptor signalling by ligand sequestration.
Nature 430:1040-1044(2004)

Cell line databases/resources FlyBase_Cell_line; FBtc9000067
Encyclopedic resources Wikidata; Q107116816
Entry history
Entry creation20-May-2021
Last entry update29-Jun-2023
Version number5