Cellosaurus cell line UM-SCC-10BPT (CVCL

Cross-references
Cell line name	UM-SCC-10BPT
Synonyms	10BPT; 10B PT
Accession	CVCL_A5TP
Resource Identification Initiative	To cite this cell line use: UM-SCC-10BPT (RRID:CVCL_A5TP)
Comments	Selected for resistance to: ChEBI; CHEBI_27899; Cisplatin (CDDP). Derived from site: Metastatic; Submental lymph node; UBERON=UBERON_0016397.
Sequence variations	Mutation; HGNC; HGNC:11998; TP53; None_reported; -; Zygosity=- (PubMed=16020667).
Disease	Laryngeal squamous cell carcinoma (NCIt: C4044) Squamous cell carcinoma of the larynx (ORDO: Orphanet_494550)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_7714 (UM-SCC-10B)
Sex of cell	Male
Age at sampling	58Y
Category	Cancer cell line
Publications	PubMed=16020667; DOI=10.1158/1535-7163.MCT-05-0081 Joshua A. Bauer, Douglas K. Trask, Bhavna Kumar, Gerrit Los, Jason Castro, Julia Shin-Jung Lee, Jian-Yong Chen, Shao-Meng Wang, Carol R. Bradford, Thomas E. Carey; Reversal of cisplatin resistance with a BH3 mimetic, (-)-gossypol, in head and neck cancer cells: role of wild-type p53 and Bcl-xL. Mol. Cancer Ther. 4:1096-1104(2005)
Encyclopedic resources	Wikidata; Q107117255
Entry history
Entry creation	20-May-2021
Last entry update	19-Dec-2024
Version number	5