Cellosaurus cell line KMS-34-SCC2 (CVCL

Cross-references
Cell line name	KMS-34-SCC2
Synonyms	KMS34-SCC2; SCC2
Accession	CVCL_A5SB
Resource Identification Initiative	To cite this cell line use: KMS-34-SCC2 (RRID:CVCL_A5SB)
Comments	Population: Japanese. Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175. Cell type: Plasma cell; CL=CL_0000786.
Sequence variations	Mutation; HGNC; HGNC:11998; TP53; Simple; p.Trp146Ter (c.438G>A); ClinVar=VCV000428890; Zygosity=Homozygous (from parent cell line).
Disease	Plasma cell myeloma (NCIt: C3242) Multiple myeloma (ORDO: Orphanet_29073)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_2996 (KMS-34)
Sex of cell	Female
Age at sampling	60Y
Category	Cancer cell line
Publications	PubMed=29045832; DOI=10.1016/j.celrep.2017.09.078; PMCID=PMC5706555 Teresa Ezponda, Daphne Dupere-Richer, Christine M. Will, Eliza C. Small, Nobish Varghese, Tej Patel, Behnam Nabet, Relja Popovic, Jon Oyer, Marinka Bulic, Yu-Peng Zheng ...Show all 20 authors... , Xiao-Xiao Huang, Mrinal Y. Shah, Sayantan Maji, Alberto Riva, Manuela Occhionorelli, Giovanni Tonon, Neil L. Kelleher, Jonathan J. Keats, Jonathan D. Licht; Show fewer authors UTX/KDM6A loss enhances the malignant phenotype of multiple myeloma and sensitizes cells to EZH2 inhibition. Cell Rep. 21:628-640(2017)
Cell line databases/resources	cancercelllines; CVCL_A5SB
Encyclopedic resources	Wikidata; Q107115594
Entry history
Entry creation	20-May-2021
Last entry update	14-Aug-2025
Version number	8