Cellosaurus logo
expasy logo

Cellosaurus UKAi008-A (CVCL_A5NB)

[Text version]
Cell line name UKAi008-A
Synonyms P15_wt37; Patient 3 control 1
Accession CVCL_A5NB
Resource Identification Initiative To cite this cell line use: UKAi008-A (RRID:CVCL_A5NB)
Comments From: Universitatsklinikum Aachen; Aachen; Germany.
Characteristics: Established from a patient that has a KIT p.Asp816Val mutation, but this cell line does not contain this mutation.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
Disease Systemic mastocytosis (NCIt: C9235)
Systemic mastocytosis (ORDO: Orphanet_2467)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_A5NC ! UKAi008-B
CVCL_A5ND ! UKAi008-C
Sex of cell Male
Age at sampling 61Y
Category Induced pluripotent stem cell
Publications

PubMed=33512435; DOI=10.1182/blood.2019004509
Szymanski de Toledo M.A., Gatz M., Sontag S., Gleixner K.V., Eisenwort G., Feldberg K., Hamouda A.E.I., Kluge F., Guareschi R., Rossetti G., Sechi A.S., Dufva O.M.J., Mustjoki S.M., Maurer A., Schuler H.M., Goetzke R., Braunschweig T., Kaiser A., Panse J., Jawhar M., Reiter A., Hilberg F., Ettmayer P., Wagner W., Koschmieder S., Brummendorf T.H., Valent P., Chatain N., Zenke M.
Nintedanib targets KIT D816V neoplastic cells derived from induced pluripotent stem cells of systemic mastocytosis.
Blood 137:2070-2084(2021)

Cross-references
Cell line databases/resources hPSCreg; UKAi008-A
Biological sample resources BioSamples; SAMEA8268473
Encyclopedic resources Wikidata; Q107117231
Entry history
Entry creation20-May-2021
Last entry update29-Jun-2023
Version number4