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Cellosaurus BW5147.PHAR2.1 (CVCL_A5JZ)

[Text version]
Cell line name BW5147.PHAR2.1
Synonyms BW5147-PHAR2.1; PHAR2.1; PhaR2.1
Accession CVCL_A5JZ
Resource Identification Initiative To cite this cell line use: BW5147.PHAR2.1 (RRID:CVCL_A5JZ)
Comments Characteristics: Deficient in alpha-mannoside beta-1,6-N-acetylglucosaminyltransferase (Mgat5) (PubMed=6216250).
Selected for resistance to: UniProtKB; P05087; Phaseolus vulgaris leucoagglutinating phytohemagglutinin (PHA-L).
Derived from site: In situ; Thymus; UBERON=UBERON_0002370.
Disease Mouse lymphoma (NCIt: C21602)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: AKR/J.
Hierarchy Parent: CVCL_3896 (BW5147)
Category Cancer cell line
Publications

PubMed=710496; DOI=10.1002/eji.1830081009
Trowbridge I.S., Hyman R., Ferson T., Mazauskas C.
Expression of Thy-1 glycoprotein on lectin-resistant lymphoma cell lines.
Eur. J. Immunol. 8:716-723(1978)

PubMed=6216250; DOI=10.1016/S0021-9258(18)33465-3
Cummings R.D., Trowbridge I.S., Kornfeld S.A.
A mouse lymphoma cell line resistant to the leukoagglutinating lectin from Phaseolus vulgaris is deficient in UDP-GlcNAc:alpha-D-mannoside beta 1,6 N-acetylglucosaminyltransferase.
J. Biol. Chem. 257:13421-13427(1982)

Cross-references
Encyclopedic resources Wikidata; Q107113526
Entry history
Entry creation20-May-2021
Last entry update29-Jun-2023
Version number4