Cellosaurus cell line HEK293 HADH-/- (CVCL

Cross-references
Cell line name	HEK293 HADH-/-
Synonyms	HEK293 SCHAD KO
Accession	CVCL_A5IP
Resource Identification Initiative	To cite this cell line use: HEK293 HADH-/- (RRID:CVCL_A5IP)
Comments	Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:4799; HADH. Transformant: NCBI_TaxID; 28285; Human adenovirus C serotype 5. Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_0045 (HEK293)
Sex of cell	Female
Age at sampling	Fetus
Category	Transformed cell line
Publications	PubMed=32876354; DOI=10.1002/jimd.12309 Kelly Velasco, Johanna L. St-Louis, Henrikke Nielsen Hovland, Nels Thompson, Asta Ottesen, Man Hung Choi, Line Pedersen, Pal Rasmus Njolstad, Thomas Arnesen, Karianne Fjeld, Ingvild Aukrust ...Show all 13 authors... , Line Merethe Myklebust, Anders Molven; Show fewer authors Functional evaluation of 16 SCHAD missense variants: only amino acid substitutions causing congenital hyperinsulinism of infancy lead to loss-of-function phenotypes in vitro. J. Inherit. Metab. Dis. 44:240-252(2021)
Encyclopedic resources	Wikidata; Q107115304
Entry history
Entry creation	20-May-2021
Last entry update	14-Aug-2025
Version number	6