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Cellosaurus TS603 (CVCL_A5HW)

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Cell line name TS603
Accession CVCL_A5HW
Resource Identification Initiative To cite this cell line use: TS603 (RRID:CVCL_A5HW)
Comments Doubling time: ~7 days (Direct_author_submission).
Miscellaneous: STR profile and doubling time from MSKCC antibody and bioresource core facility.
Derived from site: In situ; Brain; UBERON=UBERON_0000955.
Sequence variations
Disease Anaplastic oligodendroglioma (NCIt: C4326)
Anaplastic oligodendroglioma (ORDO: Orphanet_251630)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Category Cancer cell line
STR profile Source(s): Direct_author_submission

Markers:
AmelogeninX
CSF1PO12
D1S165611,15
D2S44110,11.3
D2S133817,25
D3S135816,18
D5S81811,13
D7S82010
D8S117914,15
D10S124813,16
D12S39120,22
D13S3178,9
D16S53912
D18S5114,16
D19S43315.2
D21S1129,32.2
D22S104516
FGA20,21
Penta D8,14
Penta E16
TH017,9.3
TPOX9,10
vWA16,18

Run an STR similarity search on this cell line
Web pages Provider; MSKCC; -; https://www.mskcc.org/research-advantage/support/technology/tangible-material/ts603-human-brain-cancer-glioblastoma-cell-line
Publications

PubMed=23558169; DOI=10.1126/science.1236062; PMCID=PMC3985613
Daniel Rohle, Janeta Popovici-Muller, Nicolaos Palaskas, Sevin Turcan, Christian Grommes, Carl Campos, Jennifer Tsoi, Owen Clark, Barbara Oldrini, Evangelia Komisopoulou, Kaiko Kunii ...Show all 28 authors... , Alicia Pedraza, Stefanie Schalm, Lee Silverman, Alexandra Miller, Fang Wang, Hua Yang, Yue Chen, Andrew Kernytsky, Marc K. Rosenblum, Wei Liu, Scott A. Biller, Shinsan M. Su, Cameron W. Brennan, Timothy A. Chan, Thomas G. Graeber, Katharine E. Yen, Ingo K. Mellinghoff; Show fewer authors
An inhibitor of mutant IDH1 delays growth and promotes differentiation of glioma cells.
Science 340:626-630(2013)

PubMed=33504762; DOI=10.1038/s41467-020-20752-6; PMCID=PMC7840755
Adrian Lita, Artem Pliss, Andrey N. Kuzmin, Tomohiro Yamasaki, Lu-Min Zhang, Tyrone Dowdy, Christina Burks, Natalia de Val, Orieta Celiku, Victor Ruiz-Rodado, Elena-Raluca Nicoli ...Show all 20 authors... , Michael J. Kruhlak, Thorkell Andresson, Sudipto Das, Chun-Zhang Yang, Rebecca Schmitt, Christel Herold-Mende, Mark R. Gilbert, Paras Nath Prasad, Mioara Larion; Show fewer authors
IDH1 mutations induce organelle defects via dysregulated phospholipids.
Nat. Commun. 12:614.1-614.16(2021)

Cross-references
Cell line databases/resources cancercelllines; CVCL_A5HW
Encyclopedic resources Wikidata; Q107117130
Entry history
Entry creation20-May-2021
Last entry update10-Apr-2025
Version number7