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Cellosaurus NCH1681 (CVCL_A5HV)

[Text version]
Cell line name NCH1681
Accession CVCL_A5HV
Resource Identification Initiative To cite this cell line use: NCH1681 (RRID:CVCL_A5HV)
Comments Group: Cancer stem cell line.
Derived from site: In situ; Brain; UBERON=UBERON_0000955.
Sequence variations
  • Mutation; HGNC; 5382; IDH1; Simple; p.Arg132His (c.395G>A); ClinVar=VCV000156444; Zygosity=Unspecified (PubMed=33504762).
Disease Glioblastoma (NCIt: C3058)
Glioblastoma (ORDO: Orphanet_360)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Category Cancer cell line
Publications

PubMed=29563135; DOI=10.1158/1078-0432.CCR-17-1839
Dettling S., Stamova S., Warta R., Schnolzer M., Rapp C., Rathinasamy A., Reuss D., Pocha K., Roesch S., Jungk C., Warnken U., Eckstein V., Grabe N., Schramm C., Weigand M.A., von Deimling A., Unterberg A., Beckhove P., Herold-Mende C.
Identification of CRKII, CFL1, CNTN1, NME2, and TKT as novel and frequent T-cell targets in human IDH-mutant glioma.
Clin. Cancer Res. 24:2951-2962(2018)

PubMed=33504762; DOI=10.1038/s41467-020-20752-6
Lita A., Pliss A., Kuzmin A., Yamasaki T., Zhang L.-M., Dowdy T., Burks C., de Val N., Celiku O., Ruiz-Rodado V., Nicoli E.-R., Kruhlak M., Andresson T., Das S., Yang C.-Z., Schmitt R., Herold-Mende C., Gilbert M.R., Prasad P.N., Larion M.
IDH1 mutations induce organelle defects via dysregulated phospholipids.
Nat. Commun. 12:614.1-614.16(2021)

Cross-references
Cell line databases/resources cancercelllines; CVCL_A5HV
Encyclopedic resources Wikidata; Q107116533
Entry history
Entry creation20-May-2021
Last entry update05-Oct-2023
Version number5