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Cellosaurus HES-3 NKX2.1GFP/w (CVCL_A5HB)

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Cell line name HES-3 NKX2.1GFP/w
Synonyms NKX2.1GFP/w HES3; NKX2.1(GFP/w) HES3; HES3-NKX2.1-GFP
Accession CVCL_A5HB
Resource Identification Initiative To cite this cell line use: HES-3 NKX2.1GFP/w (RRID:CVCL_A5HB)
Comments Registration: Swiss research registry; BAG-hES-IMP-0067.
Characteristics: Using homologous recombination an EGFP reporter gene was introduced in one allele of the NKX2.1 locus.
Genetic integration: Method=Homologous recombination; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP).
Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
Cell type: Embryonic stem cell; CL=CL_0002322.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_7158 (HES-3)
Children:
CVCL_A5HA (ESIBIe003-A-6)
Sex of cell Female
Age at sampling Blastocyst stage
Category Embryonic stem cell
Publications

PubMed=21425409; DOI=10.1002/stem.587
Adam L. Goulburn, Darym Alden, Richard Paul Davis, Suzanne J. Micallef, Elizabeth S. Ng, Qing C. Yu, Sue Mei Lim, Chew-Li Soh, David A. Elliott, Tanya Hatzistavrou, Justin Bourke ...Show all 20 authors... , Bradley Watmuff, Richard J. Lang, John Michael Haynes, Colin William Pouton, Antonietta Giudice, Alan Osborne Trounson, Stewart A. Anderson, Edouard G. Stanley, Andrew George Elefanty; Show fewer authors
A targeted NKX2.1 human embryonic stem cell reporter line enables identification of human basal forebrain derivatives.
Stem Cells 29:462-473(2011)

Cross-references
Encyclopedic resources Wikidata; Q107115341
Entry history
Entry creation20-May-2021
Last entry update14-Aug-2025
Version number6