Cellosaurus logo
expasy logo

Cellosaurus FAIK3-5 (CVCL_A5EC)

[Text][XML][JSON]
Cell line name FAIK3-5
Synonyms Fibroblastoid Atypical Interstitial Kidney 3-5
Accession CVCL_A5EC
Resource Identification Initiative To cite this cell line use: FAIK3-5 (RRID:CVCL_A5EC)
Comments Characteristics: Produces Epo under hypoxia.
Doubling time: ~20-30 hours (DSMZ=ACC-861).
Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Omics: Transcriptomics; RNAseq.
Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
Breed/subspecies: B6D2;C57BL/6N-Tg(EPO::Cre)1hw x B6.Cg-Gt(ROSA)26Sor/J).
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Sex of cell Female
Category Transformed cell line
Publications

PubMed=30502050; DOI=10.1016/j.kint.2018.08.043
Faik Imeri, Karen A. Nolan, Andreas M. Bapst, Sara Santambrogio, Irene Abreu-Rodriguez, Patrick Spielmann, Svende Pfundstein, Silvana Libertini, Lisa M. Crowther, Ilaria Maria Christina Orlando, Sophie Luise Dahl ...Show all 19 authors... , Anna Keodara, Willy Kuo, Vartan Kurtcuoglu, Carsten C. Scholz, Wei-Hong Qi, Edith Hummler, David Hoogewijs, Roland H. Wenger; Show fewer authors
Generation of renal Epo-producing cell lines by conditional gene tagging reveals rapid HIF-2 driven Epo kinetics, cell autonomous feedback regulation, and a telocyte phenotype.
Kidney Int. 95:375-387(2019)

Cross-references
Cell line collections (Providers) DSMZ; ACC-861
Cell line databases/resources DSMZCellDive; ACC-861
Encyclopedic resources Wikidata; Q107114956
Entry history
Entry creation20-May-2021
Last entry update14-Aug-2025
Version number9