Cellosaurus cell line 2T3 (CVCL

Cross-references
Cell line name	2T3
Accession	CVCL_A5DA
Resource Identification Initiative	To cite this cell line use: 2T3 (RRID:CVCL_A5DA)
Comments	Genetic integration: Method=Transgenic mouse; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen. Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40). Derived from site: In situ; Bone, calvaria; UBERON=UBERON_0004339. Cell type: Osteoblast; CL=CL_0000062.
Species of origin	Mus musculus (Mouse) (NCBI Taxonomy: 10090) Breed/subspecies: Bmp2 promoter T-Ag-3 transgenic.
Sex of cell	Sex unspecified
Age at sampling	7W
Category	Transformed cell line
Publications	PubMed=8536632; DOI=10.1210/endo.137.1.8536632 Nandini Ghosh-Choudhury, Jolene J. Windle, Barbara A. Koop, Marie A. Harris, Daniel L. Guerrero, John M. Wozney, Gregory Robert Mundy, Stephen E. Harris; Immortalized murine osteoblasts derived from BMP 2-T-antigen expressing transgenic mice. Endocrinology 137:331-339(1996) PubMed=16738320; DOI=10.1128/mcb.02120-05; PMCID=PMC1489126 Ke-Qin Zhang, Cielo Barragan-Adjemian, Ling Ye, Shiva Kotha, Mark Dallas, Yong-Bo Lu, Shu-Jie Zhao, Marie Harris, Stephen E. Harris, Jian Q. Feng, Lynda Faye Bonewald; E11/gp38 selective expression in osteocytes: regulation by mechanical strain and role in dendrite elongation. Mol. Cell. Biol. 26:4539-4552(2006)
Anatomy/cell type resources	BTO; BTO_0004325
Encyclopedic resources	Wikidata; Q107113222
Entry history
Entry creation	20-May-2021
Last entry update	14-Aug-2025
Version number	8