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Cellosaurus 2T3 (CVCL_A5DA)

[Text version]
Cell line name 2T3
Accession CVCL_A5DA
Resource Identification Initiative To cite this cell line use: 2T3 (RRID:CVCL_A5DA)
Comments Genetic integration: Method=Transgenic mouse; Gene=UniProtKB; P03070; SV40 large T antigen.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Bone, calvaria; UBERON=UBERON_0004339.
Cell type: Osteoblast; CL=CL_0000062.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: Bmp2 promoter T-Ag-3 transgenic.
Sex of cell Sex unspecified
Age at sampling 7W
Category Transformed cell line
Publications

PubMed=8536632; DOI=10.1210/endo.137.1.8536632
Ghosh-Choudhury N., Windle J.J., Koop B.A., Harris M.A., Guerrero D.L., Wozney J.M., Mundy G.R., Harris S.E.
Immortalized murine osteoblasts derived from BMP 2-T-antigen expressing transgenic mice.
Endocrinology 137:331-339(1996)

PubMed=16738320; DOI=10.1128/mcb.02120-05; PMCID=PMC1489126
Zhang K.-Q., Barragan-Adjemian C., Ye L., Kotha S., Dallas M., Lu Y.-B., Zhao S.-J., Harris M., Harris S.E., Feng J.Q., Bonewald L.F.
E11/gp38 selective expression in osteocytes: regulation by mechanical strain and role in dendrite elongation.
Mol. Cell. Biol. 26:4539-4552(2006)

Cross-references
Anatomy/cell type resources BTO; BTO_0004325
Encyclopedic resources Wikidata; Q107113222
Entry history
Entry creation20-May-2021
Last entry update19-Dec-2024
Version number7