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Cellosaurus HCCLM9 (CVCL_A5CU)

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Cell line name HCCLM9
Synonyms HCCLM-9; LM9
Accession CVCL_A5CU
Resource Identification Initiative To cite this cell line use: HCCLM9 (RRID:CVCL_A5CU)
Comments Population: Chinese.
Characteristics: Established from pulmonary metastatic lesions produced in nude mice by 9 rounds of subcutaneous inoculation of parent cell line.
Transformant: NCBI_TaxID; 10407; Hepatitis B virus (HBV).
Sequence variations
  • Mutation; HGNC; HGNC:14310; BRD7; Simple; p.Glu277Glyfs*18 (c.830_831delAG); Zygosity=Unspecified (from parent cell line).
  • Mutation; HGNC; HGNC:23177; KEAP1; Simple; p.Pro445Glnfs*13 (c.1334delC); Zygosity=Unspecified (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Glu51Ter (c.151G>T); ClinVar=VCV000568781; Zygosity=Unspecified (from parent cell line).
Disease Adult hepatocellular carcinoma (NCIt: C7956)
Adult hepatocellular carcinoma (ORDO: Orphanet_210159)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_7680 (HCCLM6)
Sex of cell Male
Age at sampling 39Y
Category Cancer cell line
Publications

PubMed=23904371; DOI=10.1007/s11596-013-1152-5
Min Fang, Chun-Wei Peng, Shao-Ping Liu, Jing-Ping Yuan, Yan Li;
In vitro invasive pattern of hepatocellular carcinoma cell line HCCLM9 based on three-dimensional cell culture and quantum dots molecular imaging.
J. Huazhong Univ. Sci. Technolog. Med. Sci. 33:520-524(2013)

PubMed=32884988; DOI=10.1016/j.gendis.2019.12.008; PMCID=PMC7452459
Yu-Lin Lin, Yan Li;
Study on the hepatocellular carcinoma model with metastasis.
Genes Dis. 7:336-350(2020)

Cross-references
Cell line databases/resources cancercelllines; CVCL_A5CU
Anatomy/cell type resources BTO; BTO_0006452
Encyclopedic resources Wikidata; Q107115247
Entry history
Entry creation20-May-2021
Last entry update19-Dec-2024
Version number5