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Cellosaurus Bm7 (CVCL_A5BS)

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Cell line name Bm7
Synonyms BM7
Accession CVCL_A5BS
Resource Identification Initiative To cite this cell line use: Bm7 (RRID:CVCL_A5BS)
Comments Population: Chinese; Taiwan.
Characteristics: Metastatic to brain. Established from intracardiac injection of parent cell in SCID mice and cultured from brain tissue.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P08659; Photinus pyralis firefly-type luciferase.
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Disease Lung adenocarcinoma (NCIt: C3512)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_A5BR (CL1-5-F4-Luc)
Children:
CVCL_A5BT (Bm7brm)
Sex of cell Male
Age at sampling 64Y
Category Cancer cell line
Publications

PubMed=24705471; DOI=10.1371/journal.pone.0094065; PMCID=PMC3976390
Yuh-Pyng Sher, Li-Ju Wang, Li-Ling Chuang, Mong-Hsun Tsai, Ting-Ting Kuo, Cheng-Chung Huang, Eric Y. Chuang, Liang-Chuan Lai;
ADAM9 up-regulates N-cadherin via miR-218 suppression in lung adenocarcinoma cells.
PLoS ONE 9:e94065.1-e94065.12(2014)

PubMed=25060522; DOI=10.1158/0008-5472.CAN-13-2995
Chen-Yuan Lin, Hung-Jen Chen, Cheng-Chung Huang, Liang-Chuan Lai, Tzu-Pin Lu, Guan-Chin Tseng, Ting-Ting Kuo, Qian-Yu Kuok, Jennifer L. Hsu, Shian-Ying Sung, Mien-Chie Hung, Yuh-Pyng Sher;
ADAM9 promotes lung cancer metastases to brain by a plasminogen activator-based pathway.
Cancer Res. 74:5229-5243(2014)

Cross-references
Anatomy/cell type resources BTO; BTO_0006333
Encyclopedic resources Wikidata; Q107113470
Entry history
Entry creation20-May-2021
Last entry update14-Aug-2025
Version number7