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Cellosaurus Vero 2.2 (CVCL_A5BG)

[Text version]
Cell line name Vero 2.2
Synonyms Vero 2-2; VERO 2-2; 2-2
Accession CVCL_A5BG
Resource Identification Initiative To cite this cell line use: Vero 2.2 (RRID:CVCL_A5BG)
Comments Group: Non-human primate cell line.
Transfected with: UniProtKB; Q9J0X9; Human herpesvirus 1 (isolate KOS) ICP27 (UL54).
Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
Derived from site: In situ; Kidney, epithelium; UBERON=UBERON_0004819.
Cell type: Epithelial cell of kidney; CL=CL_0002518.
Species of origin Chlorocebus sabaeus (Green monkey) (Cercopithecus sabaeus) (NCBI Taxonomy: 60711)
Hierarchy Parent: CVCL_0059 (Vero)
Sex of cell Female
Age at sampling Adult
Category Spontaneously immortalized cell line

PubMed=2846867; DOI=10.1128/JVI.62.12.4510-4522.1988
Sekulovich R.E., Leary K., Sandri-Goldin R.M.
The herpes simplex virus type 1 alpha protein ICP27 can act as a trans-repressor or a trans-activator in combination with ICP4 and ICP0.
J. Virol. 62:4510-4522(1988)

PubMed=9371577; DOI=10.1128/JVI.71.12.9188-9197.1997
Soliman T.M., Sandri-Goldin R.M., Silverstein S.J.
Shuttling of the herpes simplex virus type 1 regulatory protein ICP27 between the nucleus and cytoplasm mediates the expression of late proteins.
J. Virol. 71:9188-9197(1997)

PubMed=10074128; DOI=10.1128/JVI.73.4.2803-2813.1999
Aubert M., Blaho J.A.
The herpes simplex virus type 1 regulatory protein ICP27 is required for the prevention of apoptosis in infected human cells.
J. Virol. 73:2803-2813(1999)

Anatomy/cell type resources BTO; BTO:0006289
Encyclopedic resources Wikidata; Q107117397
Entry history
Entry creation20-May-2021
Last entry update05-Oct-2023
Version number5