Cellosaurus cell line Vero 2.2 (CVCL

Cellosaurus Vero 2.2 (CVCL_A5BG)

Cross-references
Cell line name	Vero 2.2
Synonyms	Vero 2-2; VERO 2-2; 2-2
Accession	CVCL_A5BG
Resource Identification Initiative	To cite this cell line use: Vero 2.2 (RRID:CVCL_A5BG)
Comments	Group: Non-human primate cell line. Genetic integration: Method=Transfection; Gene=UniProtKB; Q9J0X9; Human herpesvirus 1 (isolate KOS) ICP27 (UL54). Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo. Derived from site: In situ; Kidney, epithelium; UBERON=UBERON_0004819. Cell type: Epithelial cell of kidney; CL=CL_0002518.
Species of origin	Chlorocebus sabaeus (Green monkey) (Simia sabaea) (NCBI Taxonomy: 60711)
Hierarchy	Parent: CVCL_0059 (Vero)
Sex of cell	Female
Age at sampling	Adult
Category	Spontaneously immortalized cell line
Publications	PubMed=2846867; DOI=10.1128/JVI.62.12.4510-4522.1988; PMCID=PMC253561 Sekulovich R.E., Leary K., Sandri-Goldin R.M. The herpes simplex virus type 1 alpha protein ICP27 can act as a trans-repressor or a trans-activator in combination with ICP4 and ICP0. J. Virol. 62:4510-4522(1988) PubMed=9371577; DOI=10.1128/JVI.71.12.9188-9197.1997; PMCID=PMC230221 Soliman T.M., Sandri-Goldin R.M., Silverstein S.J. Shuttling of the herpes simplex virus type 1 regulatory protein ICP27 between the nucleus and cytoplasm mediates the expression of late proteins. J. Virol. 71:9188-9197(1997) PubMed=10074128; DOI=10.1128/JVI.73.4.2803-2813.1999; PMCID=PMC104038 Aubert M., Blaho J.A. The herpes simplex virus type 1 regulatory protein ICP27 is required for the prevention of apoptosis in infected human cells. J. Virol. 73:2803-2813(1999)
Anatomy/cell type resources	BTO; BTO_0006289
Encyclopedic resources	Wikidata; Q107117397
Entry history
Entry creation	20-May-2021
Last entry update	10-Apr-2025
Version number	8