Cellosaurus cell line Rev1-iPSC (CVCL

Cellosaurus Rev1-iPSC (CVCL_A4TS)

Cross-references
Cell line name	Rev1-iPSC
Accession	CVCL_A4TS
Resource Identification Initiative	To cite this cell line use: Rev1-iPSC (RRID:CVCL_A4TS)
Comments	From: Department of Biochemistry, Tokyo Dental College; Tokyo; Japan. Derived from site: In situ; Oral cavity, oral mucosa; UBERON=UBERON_0003729.
Sequence variations	Mutation; HGNC; HGNC:10472; RUNX2; Simple_corrected; p.Arg391Ter (c.1171C>T); ClinVar=VCV000065625; Zygosity=Heterozygous; Note=By CRISPR/Cas9 (PubMed=29357927).
Disease	Cleidocranial dysplasia (NCIt: C75020) Cleidocranial dysplasia (ORDO: Orphanet_1452)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_A4TH (CCD1-iPS 2)
Sex of cell	Female
Age at sampling	Age unspecified
Category	Induced pluripotent stem cell
Publications	PubMed=29357927; DOI=10.1186/s13287-017-0754-4; PMCID=PMC5778688 Akiko Saito, Akio Ooki, Takashi Nakamura, Shoko Onodera, Kamichika Hayashi, Daigo Hasegawa, Takahito Okudaira, Katsuhito Watanabe, Hiroshi Kato, Takeshi Onda, Akira Watanabe ...Show all 19 authors... , Kenjiro Kosaki, Ken Nishimura, Manami Ohtaka, Mahito Nakanishi, Teruo Sakamoto, Akira Yamaguchi, Kenji Sueishi, Toshifumi Azuma; Show fewer authors Targeted reversion of induced pluripotent stem cells from patients with human cleidocranial dysplasia improves bone regeneration in a rat calvarial bone defect model. Stem Cell Res. Ther. 9:12.1-12.10(2018)
Cell line databases/resources	SKIP; SKIP003022
Encyclopedic resources	Wikidata; Q107116736
Entry history
Entry creation	20-May-2021
Last entry update	19-Dec-2024
Version number	5