Cellosaurus cell line ZW-hiPSC 6 (CVCL

Cellosaurus ZW-hiPSC 6 (CVCL_A4GZ)

Cross-references
Cell line name	ZW-hiPSC 6
Synonyms	ZW6
Accession	CVCL_A4GZ
Resource Identification Initiative	To cite this cell line use: ZW-hiPSC 6 (RRID:CVCL_A4GZ)
Comments	From: Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Fudan University; Shanghai; China. Population: Chinese. Derived from site: In situ; Skin, dermis; UBERON=UBERON_0002067. Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations	Mutation; HGNC; HGNC:9386; PRKAG2; Simple; p.Arg302Gln (c.905G>A); ClinVar=VCV000006846; Zygosity=Heterozygous (PubMed=29452156).
Disease	Familial hypertrophic cardiomyopathy type 6 (NCIt: C177249) Rare familial disorder with hypertrophic cardiomyopathy (ORDO: Orphanet_99739)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual	CVCL_A4HA ! ZW-hiPSC 9 CVCL_A4HB ! ZW-hiPSC 12
Sex of cell	Male
Age at sampling	28Y
Category	Induced pluripotent stem cell
Publications	PubMed=29452156; DOI=10.1016/j.yjmcc.2018.02.007 Yong-Kun Zhan, Xiao-Lei Sun, Bin Li, Huan-Huan Cai, Chen Xu, Qian-Qian Liang, Chao Lu, Rui-Zhe Qian, Si-Feng Chen, Lian-Hua Yin, Wei Sheng ...Show all 15 authors... , Guo-Ying Huang, Ai-Jun Sun, Jun-Bo Ge, Ning Sun; Show fewer authors Establishment of a PRKAG2 cardiac syndrome disease model and mechanism study using human induced pluripotent stem cells. J. Mol. Cell. Cardiol. 117:49-61(2018)
Cell line databases/resources	SKIP; SKIP003131
Encyclopedic resources	Wikidata; Q105511873
Entry history
Entry creation	12-Jan-2021
Last entry update	19-Dec-2024
Version number	6