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Cellosaurus U2OS PLEC KO (CVCL_A4GM)

[Text version]
Cell line name U2OS PLEC KO
Accession CVCL_A4GM
Resource Identification Initiative To cite this cell line use: U2OS PLEC KO (RRID:CVCL_A4GM)
Comments Population: Caucasian.
Knockout cell: Method=CRISPR/Cas9; HGNC; 9069; PLEC.
Miscellaneous: Cell line information from personal communication of Laflamme C.
Derived from site: In situ; Bone, tibia; UBERON=UBERON_0000979.
Sequence variations
  • Mutation; HGNC; 9277; PPM1D; Simple; p.Arg458Ter (c.1372C>T); ClinVar=VCV002445214; Zygosity=Heterozygous (from parent cell line).
Disease Osteosarcoma (NCIt: C9145)
Osteosarcoma (ORDO: Orphanet_668)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0042 (U2OS)
Sex of cell Female
Age at sampling 15Y
Category Cancer cell line
Encyclopedic resources Wikidata; Q105511305
Entry history
Entry creation12-Jan-2021
Last entry update05-Oct-2023
Version number6