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Cellosaurus ihVFE-E67T4 (CVCL_A4EX)

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Cell line name ihVFE-E67T4
Synonyms immortalized hVFE-E67T4; immortalized human Vocal Fold Epithelial cell line-E67T4; E67T4
Accession CVCL_A4EX
Resource Identification Initiative To cite this cell line use: ihVFE-E67T4 (RRID:CVCL_A4EX)
Comments Karyotypic information: Shows trisomy 7, trisomy 20, loss of one copy of chromosome 11, and gain of two marker chromosomes of unknown origin (PubMed=33428261).
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Miscellaneous: STR profile and cell line name from personal communication of Thibeault, Susan L.
Derived from site: In situ; Larynx, vocal fold; UBERON=UBERON_0003706.
Cell type: Epithelial cell; CL=CL_0000066.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 67Y
Category Telomerase immortalized cell line
STR profile Source(s): Direct_author_submission

Markers:
AmelogeninX,Y
CSF1PO10,11
D3S135816
D5S81812,13
D7S82010,11
D8S11799,15
D13S31712
D16S53912
D18S5112,15
D21S1130
FGA20,22
Penta D9,13
Penta E5,13
TH018,9.3
TPOX11
vWA15

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Publications

PubMed=33428261; DOI=10.1096/fj.202001423R; PMCID=PMC7839467
Xia Chen, Vlasta Lungova, Hai-Yan Zhang, Chitrasen Mohanty, Christina Marie Kendziorski, Susan L. Thibeault;
Novel immortalized human vocal fold epithelial cell line: in vitro tool for mucosal biology.
FASEB J. 35:e21243.1-e21243.16(2021)

Cross-references
Encyclopedic resources Wikidata; Q105509656
Entry history
Entry creation12-Jan-2021
Last entry update14-Aug-2025
Version number8