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Cellosaurus PER-377 (CVCL_A475)

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Cell line name PER-377
Synonyms PER377
Accession CVCL_A475
Resource Identification Initiative To cite this cell line use: PER-377 (RRID:CVCL_A475)
Comments Doubling time: 3.6 days (PubMed=7536459); 66 hours (PubMed=17117183).
Omics: Transcriptomics; Microarray.
Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
Disease Childhood B acute lymphoblastic leukemia (NCIt: C9140)
Precursor B-cell acute lymphoblastic leukemia (ORDO: Orphanet_99860)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_A474 ! PER-365
Sex of cell Male
Age at sampling 1Y7M
Category Cancer cell line
STR profile Source(s): PubMed=17117183

Markers:
AmelogeninX
CSF1PO11,12
D2S133819,21
D3S135816
D5S81812
D7S82011,12
D8S117912,14
D13S31712
D16S53911
D18S5114,17
D19S43313,14
D21S1131.2,32
FGA22,23
TH016,9.3
TPOX11,12
vWA14,17

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Publications

PubMed=7536459; DOI=10.1002/gcc.2870120307
Ursula R. Kees, Lynda J. Campbell, Jette Ford, Michael Lawrence Nesbit Willoughby, Susanne E. Peroni, Pamela Ruth Ranford, Olga Margaret Garson;
New translocation t(2;13)(p12;q34) and rearrangement of the MLL gene in a childhood leukemia cell line.
Genes Chromosomes Cancer 12:201-208(1995)

PubMed=7541097
Ursula R. Kees, Leonie K. Ashman;
Synergistic action of interleukin-2 and Steel factor (SLF) on a human T lymphoblastoid cell line.
Leukemia 9:1046-1050(1995)

DOI=10.1016/B978-0-12-221970-2.50457-5
Hans Gunther Drexler;
The leukemia-lymphoma cell line factsbook.
(In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001)

PubMed=12883040
Ursula R. Kees, Jette Ford, Marcia Watson, Ashleigh R. Murch, Markus Ringner, Robert L. Walker, Paul S. Meltzer;
Gene expression profiles in a panel of childhood leukemia cell lines mirror critical features of the disease.
Mol. Cancer Ther. 2:671-677(2003)

PubMed=14671638; DOI=10.1038/sj.leu.2403236
Hans Gunther Drexler, Hilmar Quentmeier, Roderick A.F. MacLeod;
Malignant hematopoietic cell lines: in vitro models for the study of MLL gene alterations.
Leukemia 18:227-232(2004)

PubMed=17117183; DOI=10.1038/sj.bjc.6603447; PMCID=PMC2360743
Alex H. Beesley, Misty-Lee Palmer, Jette Ford, Richard E. Weller, Aaron J. Cummings, Joseph R. Freitas, Martin J. Firth, Kanchana U. Perera, Nick H. de Klerk, Ursula R. Kees;
Authenticity and drug resistance in a panel of acute lymphoblastic leukaemia cell lines.
Br. J. Cancer 95:1537-1544(2006)

Cross-references
Encyclopedic resources Wikidata; Q54947186
Polymorphism and mutation databases Cosmic; 1130242
Entry history
Entry creation06-Jun-2012
Last entry update10-Apr-2025
Version number13