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Cellosaurus PER-377 (CVCL_A475)

[Text version]
Cell line name PER-377
Synonyms PER377
Accession CVCL_A475
Resource Identification Initiative To cite this cell line use: PER-377 (RRID:CVCL_A475)
Comments Doubling time: 3.6 days (PubMed=7536459); 66 hours (PubMed=17117183).
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
Disease Childhood B acute lymphoblastic leukemia (NCIt: C9140)
Precursor B-cell acute lymphoblastic leukemia (ORDO: Orphanet_99860)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_A474 ! PER-365
Sex of cell Male
Age at sampling 1Y7M
Category Cancer cell line
STR profile Source(s): PubMed=17117183

Markers:
AmelogeninX
CSF1PO11,12
D2S133819,21
D3S135816
D5S81812
D7S82011,12
D8S117912,14
D13S31712
D16S53911
D18S5114,17
D19S43313,14
D21S1131.2,32
FGA22,23
TH016,9.3
TPOX11,12
vWA14,17

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Publications

PubMed=7536459; DOI=10.1002/gcc.2870120307
Kees U.R., Campbell L.J., Ford J., Willoughby M.L.N., Peroni S.E., Ranford P.R., Garson O.M.
New translocation t(2;13)(p12;q34) and rearrangement of the MLL gene in a childhood leukemia cell line.
Genes Chromosomes Cancer 12:201-208(1995)

PubMed=7541097
Kees U.R., Ashman L.K.
Synergistic action of interleukin-2 and Steel factor (SLF) on a human T lymphoblastoid cell line.
Leukemia 9:1046-1050(1995)

DOI=10.1016/B978-0-12-221970-2.50457-5
Drexler H.G.
The leukemia-lymphoma cell line factsbook.
(In) ISBN 9780122219702; pp.1-733; Academic Press; London (2001)

PubMed=12883040
Kees U.R., Ford J., Watson M., Murch A.R., Ringner M., Walker R.L., Meltzer P.S.
Gene expression profiles in a panel of childhood leukemia cell lines mirror critical features of the disease.
Mol. Cancer Ther. 2:671-677(2003)

PubMed=14671638; DOI=10.1038/sj.leu.2403236
Drexler H.G., Quentmeier H., MacLeod R.A.F.
Malignant hematopoietic cell lines: in vitro models for the study of MLL gene alterations.
Leukemia 18:227-232(2004)

PubMed=17117183; DOI=10.1038/sj.bjc.6603447
Beesley A.H., Palmer M.-L., Ford J., Weller R.E., Cummings A.J., Freitas J.R., Firth M.J., Perera K.U., de Klerk N.H., Kees U.R.
Authenticity and drug resistance in a panel of acute lymphoblastic leukaemia cell lines.
Br. J. Cancer 95:1537-1544(2006)

Cross-references
Encyclopedic resources Wikidata; Q54947186
Polymorphism and mutation databases Cosmic; 1130242
Entry history
Entry creation06-Jun-2012
Last entry update29-Jun-2023
Version number12