Cellosaurus cell line LIM2463B (CVCL

Cross-references
Cell line name	LIM2463B
Synonyms	LIM-2463B; LIM 2463B
Accession	CVCL_A456
Resource Identification Initiative	To cite this cell line use: LIM2463B (RRID:CVCL_A456)
Comments	From: Ludwig Institute for Cancer Research, Melbourne Branch; Melbourne; Australia. Microsatellite instability: Stable (MSS) (PubMed=19378335). Derived from site: In situ; Rectum; UBERON=UBERON_0001052.
Sequence variations	Gene deletion; HGNC; HGNC:11998; TP53; Zygosity=Homozygous (PubMed=19378335). Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gln61His (c.183A>C); ClinVar=VCV000177881; Zygosity=Heterozygous (PubMed=19378335).
Disease	Rectal adenocarcinoma (NCIt: C9383)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_4440 (LIM2463)
Sex of cell	Female
Age at sampling	77Y
Category	Cancer cell line
Publications	PubMed=19378335; DOI=10.1002/ijc.24289 Zhang H.-H., Walker F.E., Kiflemariam S., Whitehead R.H., Williams D., Phillips W.A., Mikeska T., Dobrovic A., Burgess A.W. Selective inhibition of proliferation in colorectal carcinoma cell lines expressing mutant APC or activated B-Raf. Int. J. Cancer 125:297-307(2009)
Cell line databases/resources	cancercelllines; CVCL_A456 ColonAtlas; LIM2463B
Encyclopedic resources	Wikidata; Q54902537
Polymorphism and mutation databases	Cosmic; 1238056
Entry history
Entry creation	06-Jun-2012
Last entry update	19-Dec-2024
Version number	17