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Cellosaurus KMS-5 (CVCL_A446)

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Cell line name KMS-5
Synonyms KMS5; Kawasaki Medical School-5
Accession CVCL_A446
Resource Identification Initiative To cite this cell line use: KMS-5 (RRID:CVCL_A446)
Comments Population: Japanese.
Characteristics: Produces IgD lambda.
Doubling time: 24 hours (PubMed=2519219).
Omics: Variations; Array-based CGH.
Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.
Cell type: Plasma cell; CL=CL_0000786.
Disease Plasma cell myeloma (NCIt: C3242)
Multiple myeloma (ORDO: Orphanet_29073)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 80Y
Category Cancer cell line
Publications

PubMed=2519219
Takemi Ohtsuki, Yoshihito Yawata, Masayoshi Namba;
Establishment and characterization of five human myeloma cell lines.
Hum. Cell 2:297-303(1989)

PubMed=2768132; DOI=10.1007/BF02623725
Masayoshi Namba, Takemi Ohtsuki, Masaharu Mori, Atsushi Togawa, Hideho Wada, Takashi Sugihara, Yoshihito Yawata, Tetsuo Kimoto;
Establishment of five human myeloma cell lines.
In Vitro Cell. Dev. Biol. 25:723-729(1989)

PubMed=9290701; DOI=10.1002/(SICI)1098-2744(199708)19:4<243::AID-MC5>3.0.CO;2-D
Li-Qun Jia, Motonobu Osada, Chikashi Ishioka, Makio Gamo, Shuntaro Ikawa, Takao Suzuki, Hideki Shimodaira, Tomohito Niitani, Toshio Kudo, Mitoshi Akiyama, Narimiti Kimura ...Show all 18 authors... , Mitsuyoshi Matsuo, Hiroshi Mizusawa, Noriho Tanaka, Hideki Koyama, Masayoshi Namba, Ryunosuke Kanamaru, Toshio Kuroki; Show fewer authors
Screening the p53 status of human cell lines using a yeast functional assay.
Mol. Carcinog. 19:243-253(1997)

PubMed=9787181; DOI=10.1182/blood.V92.9.3410
Akira Sakai, Catherine Thieblemont, Axel Wellmann, Elaine Sarkin Jaffe, Mark Raffeld;
PTEN gene alterations in lymphoid neoplasms.
Blood 92:3410-3415(1998)

DOI=10.1007/0-306-46877-8_4
Helena Jernberg-Wiklund, Kenneth Nilsson;
Multiple myeloma cell lines.
(In book chapter) Human cell culture. Vol. 3. Cancer cell lines part 3; Masters, John R.W. & Palsson, Bernhard Orn (eds.); pp.81-155; Kluwer Academic Publishers; New York; USA (2000)

PubMed=10936422; DOI=10.1016/S0145-2126(99)00195-2
Hans Gunther Drexler, Yoshinobu Matsuo;
Malignant hematopoietic cell lines: in vitro models for the study of multiple myeloma and plasma cell leukemia.
Leuk. Res. 24:681-703(2000)

PubMed=15215163; DOI=10.1016/S0002-9440(10)63276-2; PMCID=PMC1618545
Jun Inoue, Takemi Otsuki, Akira Hirasawa, Issei Imoto, Yoshinobu Matsuo, Shiroh Shimizu, Masafumi Taniwaki, Johji Inazawa;
Overexpression of PDZK1 within the 1q12-q22 amplicon is likely to be associated with drug-resistance phenotype in multiple myeloma.
Am. J. Pathol. 165:71-81(2004)

Cross-references
Cell line databases/resources CGH-DB; 20-1
CGH-DB; 9132-4
Encyclopedic resources Wikidata; Q54900185
Polymorphism and mutation databases Cosmic; 850215
Entry history
Entry creation06-Jun-2012
Last entry update14-Aug-2025
Version number19