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Cellosaurus HDC-111 (CVCL_A375)

[Text version]
Cell line name HDC-111
Synonyms HDC111
Accession CVCL_A375
Resource Identification Initiative To cite this cell line use: HDC-111 (RRID:CVCL_A375)
Comments Doubling time: 43.98 hours (PubMed=25944804).
Omics: Deep proteome analysis.
Derived from site: In situ; Rectum; UBERON=UBERON_0001052.
Disease Rectal adenocarcinoma (NCIt: C9383)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 49Y
Category Cancer cell line
Publications

PubMed=1980607; DOI=10.1002/gcc.2870020112
Bruderlein S., van der Bosch K., Schlag P.M., Schwab M.
Cytogenetics and DNA amplification in colorectal cancers.
Genes Chromosomes Cancer 2:63-70(1990)

PubMed=18258742; DOI=10.1073/pnas.0712176105
Emaduddin M., Bicknell D.C., Bodmer W.F., Feller S.M.
Cell growth, global phosphotyrosine elevation, and c-Met phosphorylation through Src family kinases in colorectal cancer cells.
Proc. Natl. Acad. Sci. U.S.A. 105:2358-2362(2008)

PubMed=20606684; DOI=10.1038/sj.bjc.6605780
Bracht K., Nicholls A.M., Liu Y., Bodmer W.F.
5-fluorouracil response in a large panel of colorectal cancer cell lines is associated with mismatch repair deficiency.
Br. J. Cancer 103:340-346(2010)

PubMed=25944804; DOI=10.1158/1078-0432.CCR-14-2457
Bazzocco S., Dopeso H., Carton-Garcia F., Macaya I., Andretta E., Chionh F., Rodrigues P., Garrido M., Alazzouzi H., Nieto R., Sanchez A., Schwartz S. Jr., Bilic J., Mariadason J.M., Arango D.
Highly expressed genes in rapidly proliferating tumor cells as new targets for colorectal cancer treatment.
Clin. Cancer Res. 21:3695-3704(2015)

PubMed=29101300; DOI=10.15252/msb.20177701
Frejno M., Zenezini Chiozzi R., Wilhelm M., Koch H., Zheng R.-S., Klaeger S., Ruprecht B., Meng C., Kramer K., Jarzab A., Heinzlmeir S., Johnstone E., Domingo E., Kerr D., Jesinghaus M., Slotta-Huspenina J., Weichert W., Knapp S., Feller S.M., Kuster B.
Pharmacoproteomic characterisation of human colon and rectal cancer.
Mol. Syst. Biol. 13:951-951(2017)

Cross-references
Encyclopedic resources Wikidata; Q54882139
Polymorphism and mutation databases Cosmic; 715202
Proteomic databases PRIDE; PXD005354
PRIDE; PXD005355
Entry history
Entry creation06-Jun-2012
Last entry update29-Jun-2023
Version number9